HCSGD entry for SPG20
1. General information
| Official gene symbol | SPG20 |
|---|---|
| Entrez ID | 23111 |
| Gene full name | spastic paraplegia 20 (Troyer syndrome) |
| Other gene symbols | SPARTIN TAHCCP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005741 | Mitochondrial outer membrane | IDA | cellular_component |
| GO:0005811 | Lipid particle | IEA | cellular_component |
| GO:0008219 | Cell death | IEA | biological_process |
| GO:0009838 | Abscission | IMP | biological_process |
| GO:0030496 | Midbody | IDA | cellular_component |
| GO:0030514 | Negative regulation of BMP signaling pathway | IEA | biological_process |
| GO:0031625 | Ubiquitin protein ligase binding | IPI | molecular_function |
| GO:0034389 | Lipid particle organization | IEA | biological_process |
| GO:0045202 | Synapse | IEA | cellular_component |
| GO:0048698 | Negative regulation of collateral sprouting in absence of injury | IEA | biological_process |
| GO:0050905 | Neuromuscular process | IEA | biological_process |
| GO:0051301 | Cell division | IMP | biological_process |
| GO:0051881 | Regulation of mitochondrial membrane potential | IMP | biological_process |
| GO:0060612 | Adipose tissue development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8776706546 | 0.0770583336 | 0.9999902473 | 0.5246384894 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0857250165 |
| GSE13712_SHEAR | Up | 0.0081111166 |
| GSE13712_STATIC | Up | 0.1065905421 |
| GSE19018 | Up | 0.0279477523 |
| GSE19899_A1 | Down | -0.2028438269 |
| GSE19899_A2 | Down | -0.3511068031 |
| PubMed_21979375_A1 | Down | -1.0467535116 |
| PubMed_21979375_A2 | Down | -0.5898875162 |
| GSE35957 | Up | 0.1045765998 |
| GSE36640 | Up | 0.0005373063 |
| GSE54402 | Down | -0.1494248554 |
| GSE9593 | Up | 0.1264996874 |
| GSE43922 | Down | -0.4992113955 |
| GSE24585 | Down | -0.2234009306 |
| GSE37065 | Up | 0.1313346724 |
| GSE28863_A1 | Down | -0.0641803797 |
| GSE28863_A2 | Down | -0.2519330945 |
| GSE28863_A3 | Down | -0.5610192590 |
| GSE28863_A4 | Up | 0.2226863152 |
| GSE48662 | Up | 0.5095246956 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020313 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031237 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-197-3p | MIMAT0000227 | MIRT048060 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
