HCSGD entry for ZNF423
1. General information
| Official gene symbol | ZNF423 |
|---|---|
| Entrez ID | 23090 |
| Gene full name | zinc finger protein 423 |
| Other gene symbols | Ebfaz JBTS19 NPHP14 OAZ Roaz ZFP423 Zfp104 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007219 | Notch signaling pathway | IEA ISS | biological_process |
| GO:0007399 | Nervous system development | IEA | biological_process |
| GO:0030154 | Cell differentiation | IEA | biological_process |
| GO:0030513 | Positive regulation of BMP signaling pathway | IEA ISS | biological_process |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IDA IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4332527108 | 0.0252029596 | 0.9999902473 | 0.3051366605 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4932401598 |
| GSE13712_SHEAR | Down | -4.1404260279 |
| GSE13712_STATIC | Down | -1.8633409119 |
| GSE19018 | Down | -0.1156072354 |
| GSE19899_A1 | Up | 0.1597829593 |
| GSE19899_A2 | Down | -0.1738159191 |
| PubMed_21979375_A1 | Up | 0.2321887030 |
| PubMed_21979375_A2 | Up | 0.0000068232 |
| GSE35957 | Down | -0.6994618005 |
| GSE36640 | Down | -0.1725981406 |
| GSE54402 | Down | -0.2420815686 |
| GSE9593 | Down | -0.6577423539 |
| GSE43922 | Up | 0.0144796337 |
| GSE24585 | Up | 0.2925167153 |
| GSE37065 | Down | -0.2117472431 |
| GSE28863_A1 | Down | -0.0180932893 |
| GSE28863_A2 | Up | 0.0055149171 |
| GSE28863_A3 | Up | 0.3051137390 |
| GSE28863_A4 | Up | 0.1213606433 |
| GSE48662 | Up | 0.2861222692 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030310 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-17-3p | MIMAT0000071 | MIRT050769 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 26105007 | Blocking LPS-induced NF-kappaB activation and cytokine production by Bay 11-7082 failed to rescue the impaired adipogenesis and the reduction in PPARgamma and Zfp423 expression |
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