HCSGD entry for MYCBP2
1. General information
| Official gene symbol | MYCBP2 |
|---|---|
| Entrez ID | 23077 |
| Gene full name | MYC binding protein 2, E3 ubiquitin protein ligase |
| Other gene symbols | PAM |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0015630 | Microtubule cytoskeleton | IEA | cellular_component |
| GO:0021785 | Branchiomotor neuron axon guidance | IEA | biological_process |
| GO:0021952 | Central nervous system projection neuron axonogenesis | IEA | biological_process |
| GO:0030424 | Axon | IEA | cellular_component |
| GO:0032880 | Regulation of protein localization | IEA | biological_process |
| GO:0042803 | Protein homodimerization activity | IEA | molecular_function |
| GO:0051493 | Regulation of cytoskeleton organization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0074943087 | 0.9664443220 | 0.2262129587 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1245303349 |
| GSE13712_SHEAR | Up | 0.4213231817 |
| GSE13712_STATIC | Up | 0.0584056912 |
| GSE19018 | Down | -0.0228302084 |
| GSE19899_A1 | Up | 0.5125860185 |
| GSE19899_A2 | Up | 0.2376288908 |
| PubMed_21979375_A1 | Up | 0.6712522843 |
| PubMed_21979375_A2 | Up | 0.7786953509 |
| GSE35957 | Up | 0.3296245715 |
| GSE36640 | Up | 0.1999309713 |
| GSE54402 | Up | 0.1957106967 |
| GSE9593 | Up | 0.1032278842 |
| GSE43922 | Up | 0.0740117265 |
| GSE24585 | Down | -0.2475303229 |
| GSE37065 | Down | -0.0340237001 |
| GSE28863_A1 | Up | 2.3743888207 |
| GSE28863_A2 | Up | 0.5947854783 |
| GSE28863_A3 | Down | -0.0501436276 |
| GSE28863_A4 | Up | 0.1016926204 |
| GSE48662 | Up | 0.3505108908 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-21-5p | MIMAT0000076 | MIRT030878 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-15b-5p | MIMAT0000417 | MIRT046460 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-183-5p | MIMAT0000261 | MIRT047123 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-148a-3p | MIMAT0000243 | MIRT048035 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-196a-5p | MIMAT0000226 | MIRT048178 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT050846 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
