HCSGD entry for SWAP70


1. General information

Official gene symbolSWAP70
Entrez ID23075
Gene full nameSWAP switching B-cell complex 70kDa subunit
Other gene symbolsSWAP-70
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingIEAmolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0030027LamellipodiumIEAcellular_component
GO:0045190Isotype switchingIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.10122120360.91830096880.66238274921.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0482950939
GSE13712_SHEARUp0.4374037590
GSE13712_STATICUp0.1277342771
GSE19018Up0.4016366361
GSE19899_A1Down-0.1059292005
GSE19899_A2Down-0.0894133993
PubMed_21979375_A1Down-0.0432114036
PubMed_21979375_A2Up0.1508477979
GSE35957Up0.6437304150
GSE36640Down-0.0202871763
GSE54402Up0.0382427522
GSE9593Up0.6561798585
GSE43922Down-0.1669219719
GSE24585Up0.2207796544
GSE37065Up0.0037887691
GSE28863_A1Up0.2375291990
GSE28863_A2Up0.2024746657
GSE28863_A3Down-0.1002925079
GSE28863_A4Up0.2712272065
GSE48662Down-0.2598910859

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT002694Microarray//Microarray;OtherFunctional MTI (Weak)15685193
hsa-miR-145-5pMIMAT0000437MIRT006747Reporter assay;MicroarrayFunctional MTI21351259
hsa-miR-145-5pMIMAT0000437MIRT006747Reporter assay;Western blot;qRT-PCRFunctional MTI21360565
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.