HCSGD entry for HECW1

1. General information

Official gene symbolHECW1
Entrez ID23072
Gene full nameHECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
Other gene symbolsNEDL1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004842Ubiquitin-protein ligase activityIBA IEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0042787Protein ubiquitination involved in ubiquitin-dependent protein catabolic processIBAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.86115718630.64296660840.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0949058773
GSE13712_SHEARUp0.0582027979
GSE13712_STATICDown-0.0061072141
GSE19018Down-0.0815667225
GSE19899_A1Up0.0924734036
GSE19899_A2Down-0.0270704719
PubMed_21979375_A1Up0.1051406200
PubMed_21979375_A2Down-0.1475810078
GSE35957Up0.1422208406
GSE36640Up0.2538614098
GSE54402Down-0.0007918951
GSE9593Up0.0931630950
GSE43922Down-0.0846892144
GSE24585Down-0.0579715654
GSE37065Down-0.0871205641
GSE28863_A1Down-0.0912911101
GSE28863_A2Up0.0774407325
GSE28863_A3Up0.0338543155
GSE28863_A4Down-0.0389566976
GSE48662Down-0.0111131410

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.