HCSGD entry for SETD1B


1. General information

Official gene symbolSETD1B
Entrez ID23067
Gene full nameSET domain containing 1B
Other gene symbolsKMT2G Set1B
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000166Nucleotide bindingIEAmolecular_function
GO:0003676Nucleic acid bindingIEAmolecular_function
GO:0003723RNA bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0005694ChromosomeIEAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0016607Nuclear speckIEAcellular_component
GO:0018022Peptidyl-lysine methylationIDAbiological_process
GO:0018024Histone-lysine N-methyltransferase activityIEAmolecular_function
GO:0035097Histone methyltransferase complexIDAcellular_component
GO:0042800Histone methyltransferase activity (H3-K4 specific)IDAmolecular_function
GO:0048188Set1C/COMPASS complexIDAcellular_component
GO:0051568Histone H3-K4 methylationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.21326288890.39998755750.89000990961.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1192587350
GSE13712_SHEARDown-0.0423623946
GSE13712_STATICUp0.0080649166
GSE19018Down-0.7057003844
GSE19899_A1Down-0.2270154693
GSE19899_A2Up0.0836528230
PubMed_21979375_A1Down-0.4174001782
PubMed_21979375_A2Up0.3736347346
GSE35957Up0.2224108276
GSE36640Down-0.3788636162
GSE54402Down-0.0607582930
GSE9593Down-0.1422307768
GSE43922Up0.0363778376
GSE24585Up0.7137447564
GSE37065Down-0.1130995678
GSE28863_A1Up0.3683045297
GSE28863_A2Up0.3009671278
GSE28863_A3Up0.4219386099
GSE28863_A4Up0.1123352008
GSE48662Down-0.3105393077

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-151a-5pMIMAT0004697MIRT019516SequencingFunctional MTI (Weak)20371350
hsa-miR-7-5pMIMAT0000252MIRT025865SequencingFunctional MTI (Weak)20371350
hsa-miR-103a-3pMIMAT0000101MIRT027194SequencingFunctional MTI (Weak)20371350
hsa-miR-27a-3pMIMAT0000084MIRT028695SequencingFunctional MTI (Weak)20371350
hsa-miR-16-5pMIMAT0000069MIRT031924SequencingFunctional MTI (Weak)20371350
hsa-miR-484MIMAT0002174MIRT042094CLASHFunctional MTI (Weak)23622248
hsa-miR-222-3pMIMAT0000279MIRT046658CLASHFunctional MTI (Weak)23622248
hsa-miR-197-3pMIMAT0000227MIRT048081CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049485CLASHFunctional MTI (Weak)23622248
hsa-miR-25-3pMIMAT0000081MIRT050342CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.