HCSGD entry for SETX
1. General information
| Official gene symbol | SETX |
|---|---|
| Entrez ID | 23064 |
| Gene full name | senataxin |
| Other gene symbols | ALS4 AOA2 SCAR1 bA479K20.2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IC | molecular_function |
| GO:0003678 | DNA helicase activity | TAS | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | IDA | cellular_component |
| GO:0005730 | Nucleolus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006302 | Double-strand break repair | IDA | biological_process |
| GO:0006369 | Termination of RNA polymerase II transcription | IEA | biological_process |
| GO:0006396 | RNA processing | TAS | biological_process |
| GO:0007623 | Circadian rhythm | IEA | biological_process |
| GO:0008219 | Cell death | IEA | biological_process |
| GO:0032508 | DNA duplex unwinding | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0324036131 | 0.9044057293 | 0.4156410819 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0088136337 |
| GSE13712_SHEAR | Up | 0.1421525931 |
| GSE13712_STATIC | Down | -0.0873521374 |
| GSE19018 | Down | -0.3491386686 |
| GSE19899_A1 | Up | 0.1774310465 |
| GSE19899_A2 | Down | -0.2370859770 |
| PubMed_21979375_A1 | Up | 0.3128449089 |
| PubMed_21979375_A2 | Up | 0.2860780533 |
| GSE35957 | Up | 0.3566708634 |
| GSE36640 | Down | -0.1790521922 |
| GSE54402 | Up | 0.3498696978 |
| GSE9593 | Up | 0.0184574807 |
| GSE43922 | Up | 0.0362833141 |
| GSE24585 | Up | 0.0838001765 |
| GSE37065 | Up | 0.3229266226 |
| GSE28863_A1 | Up | 1.4247752461 |
| GSE28863_A2 | Up | 1.2021242694 |
| GSE28863_A3 | Down | -0.4816650224 |
| GSE28863_A4 | Up | 0.2238594197 |
| GSE48662 | Up | 0.1045687143 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT016893 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040922 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
