HCSGD entry for TNIK

1. General information

Official gene symbolTNIK
Entrez ID23043
Gene full nameTRAF2 and NCK interacting kinase
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004674Protein serine/threonine kinase activityIDA IEAmolecular_function
GO:0004702Receptor signaling protein serine/threonine kinase activityIBAmolecular_function
GO:0005083Small GTPase regulator activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005856CytoskeletonIDAcellular_component
GO:0006468Protein phosphorylationIDAbiological_process
GO:0007010Cytoskeleton organizationIMPbiological_process
GO:0007256Activation of JNKK activityIDA IEA IMPbiological_process
GO:0016055Wnt signaling pathwayIEAbiological_process
GO:0031532Actin cytoskeleton reorganizationIDA IEAbiological_process
GO:0035556Intracellular signal transductionIDAbiological_process
GO:0046777Protein autophosphorylationIDAbiological_process
GO:0048814Regulation of dendrite morphogenesisIDAbiological_process
GO:0055037Recycling endosomeIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.06226105770.56731610500.53960266711.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2448565568
GSE13712_SHEARUp0.9490793862
GSE13712_STATICUp1.4740174082
GSE19018Down-0.1857810970
GSE19899_A1Up0.0811525131
GSE19899_A2Up0.2584593308
PubMed_21979375_A1Up0.1923638930
PubMed_21979375_A2Up1.1136408580
GSE35957Up0.3874049399
GSE36640Down-0.3036886955
GSE54402Down-0.1039331468
GSE9593Down-0.0510422766
GSE43922Up0.0035933002
GSE24585Down-0.4391804051
GSE37065Up0.0516644765
GSE28863_A1Up0.0768049067
GSE28863_A2Up0.6536282636
GSE28863_A3Down-0.7194602748
GSE28863_A4Up0.0018885412
GSE48662Down-0.0792377437

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017299MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.