HCSGD entry for FOXE1

1. General information

Official gene symbolFOXE1
Entrez ID2304
Gene full nameforkhead box E1 (thyroid transcription factor 2)
Other gene symbolsFKHL15 FOXE2 HFKH4 HFKL5 TITF2 TTF-2 TTF2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterISS NASbiological_process
GO:0002089Lens morphogenesis in camera-type eyeIBAbiological_process
GO:0003677DNA bindingIDAmolecular_function
GO:0003690Double-stranded DNA bindingIBAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIDAmolecular_function
GO:0003705RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activityIBAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005667Transcription factor complexIBAcellular_component
GO:0006590Thyroid hormone generationIBA ISSbiological_process
GO:0007389Pattern specification processIBAbiological_process
GO:0008134Transcription factor bindingIBAmolecular_function
GO:0008301DNA binding, bendingIBAmolecular_function
GO:0009653Anatomical structure morphogenesisNASbiological_process
GO:0016477Cell migrationISSbiological_process
GO:0030878Thyroid gland developmentIEP IMPbiological_process
GO:0031069Hair follicle morphogenesisIBA ISSbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045892Negative regulation of transcription, DNA-templatedISSbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedIDAbiological_process
GO:0048538Thymus developmentIEPbiological_process
GO:0048562Embryonic organ morphogenesisIBA ISSbiological_process
GO:0051090Regulation of sequence-specific DNA binding transcription factor activityIBAbiological_process
GO:0060022Hard palate developmentIMPbiological_process
GO:0060023Soft palate developmentIMPbiological_process
GO:0060465Pharynx developmentIEPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.15205391510.52567145630.77862112431.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0206685449
GSE13712_SHEARDown-0.0491932414
GSE13712_STATICUp0.0457281510
GSE19018Up0.0654875295
GSE19899_A1Up0.0695037452
GSE19899_A2Down-0.0768667606
PubMed_21979375_A1Down-0.5713845442
PubMed_21979375_A2Down-0.1383192218
GSE35957Up0.2408782530
GSE36640Up2.3887622614
GSE54402Down-0.3724674620
GSE9593Up0.1130687086
GSE43922Up0.0977569731
GSE24585Up0.1959797528
GSE37065Down-0.1555786291
GSE28863_A1Down-0.0328943165
GSE28863_A2Down-0.1298536404
GSE28863_A3Up0.6545936012
GSE28863_A4Up0.1091588268
GSE48662Down-0.1722232787

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT028762MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.