HCSGD entry for USP33
1. General information
| Official gene symbol | USP33 |
|---|---|
| Entrez ID | 23032 |
| Gene full name | ubiquitin specific peptidase 33 |
| Other gene symbols | VDU1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001664 | G-protein coupled receptor binding | IPI | molecular_function |
| GO:0004197 | Cysteine-type endopeptidase activity | IMP | molecular_function |
| GO:0004221 | Ubiquitin thiolesterase activity | IDA IEA | molecular_function |
| GO:0004843 | Ubiquitin-specific protease activity | IDA TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0005794 | Golgi apparatus | IDA IEA | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0006511 | Ubiquitin-dependent protein catabolic process | IEA TAS | biological_process |
| GO:0006897 | Endocytosis | IEA | biological_process |
| GO:0007411 | Axon guidance | IEA ISS | biological_process |
| GO:0008270 | Zinc ion binding | IDA IEA | molecular_function |
| GO:0008277 | Regulation of G-protein coupled receptor protein signaling pathway | IMP | biological_process |
| GO:0016477 | Cell migration | IEA ISS | biological_process |
| GO:0016579 | Protein deubiquitination | IDA | biological_process |
| GO:0030891 | VCB complex | TAS | cellular_component |
| GO:0043130 | Ubiquitin binding | IDA | molecular_function |
| GO:0044297 | Cell body | IEA | cellular_component |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
| GO:0051298 | Centrosome duplication | IMP | biological_process |
| GO:0070536 | Protein K63-linked deubiquitination | IDA | biological_process |
| GO:0071108 | Protein K48-linked deubiquitination | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8017131986 | 0.0521646404 | 0.9999902473 | 0.4296074781 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0682124523 |
| GSE13712_SHEAR | Down | -0.1176535536 |
| GSE13712_STATIC | Down | -0.1247208132 |
| GSE19018 | Up | 0.2357356334 |
| GSE19899_A1 | Down | -0.5201886176 |
| GSE19899_A2 | Down | -0.7214833354 |
| PubMed_21979375_A1 | Down | -0.8446684626 |
| PubMed_21979375_A2 | Down | -0.5920323818 |
| GSE35957 | Up | 0.2008772616 |
| GSE36640 | Down | -0.4937451656 |
| GSE54402 | Down | -0.3735716415 |
| GSE9593 | Up | 0.0382924440 |
| GSE43922 | Down | -0.6012227068 |
| GSE24585 | Up | 0.2614926630 |
| GSE37065 | Up | 0.1653148409 |
| GSE28863_A1 | Up | 0.2565690035 |
| GSE28863_A2 | Up | 0.2786236708 |
| GSE28863_A3 | Down | -0.5074853686 |
| GSE28863_A4 | Down | -0.2389600637 |
| GSE48662 | Up | 0.3953755785 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-148b-3p | MIMAT0000759 | MIRT019307 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-1 | MIMAT0000416 | MIRT023537 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-877-5p | MIMAT0004949 | MIRT037270 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
