HCSGD entry for UNC13A

1. General information

Official gene symbolUNC13A
Entrez ID23025
Gene full nameunc-13 homolog A (C. elegans)
Other gene symbolsMunc13-1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001956Positive regulation of neurotransmitter secretionIEAbiological_process
GO:0005737CytoplasmIEAcellular_component
GO:0007528Neuromuscular junction developmentIEAbiological_process
GO:0016081Synaptic vesicle docking involved in exocytosisIEAbiological_process
GO:0016082Synaptic vesicle primingIEAbiological_process
GO:0016188Synaptic vesicle maturationIEAbiological_process
GO:0019992Diacylglycerol bindingIEAmolecular_function
GO:0030054Cell junctionIEAcellular_component
GO:0031594Neuromuscular junctionIEAcellular_component
GO:0035249Synaptic transmission, glutamatergicIEAbiological_process
GO:0035556Intracellular signal transductionIEAbiological_process
GO:0042734Presynaptic membraneIEAcellular_component
GO:0046872Metal ion bindingIEAmolecular_function
GO:0048172Regulation of short-term neuronal synaptic plasticityIEAbiological_process
GO:0050435Beta-amyloid metabolic processIEAbiological_process
GO:0060384InnervationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.04987591660.98306420350.48963916761.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1732323990
GSE13712_SHEARDown-0.1045866242
GSE13712_STATICUp0.1072106620
GSE19018Up0.1308525226
GSE19899_A1Up0.0081143321
GSE19899_A2Up0.5171533999
PubMed_21979375_A1Up0.9443360901
PubMed_21979375_A2Up0.3278436026
GSE35957Down-0.0330475303
GSE36640Down-0.0353957378
GSE54402Up0.5645897277
GSE9593Up0.1879248057
GSE43922Up0.8440900409
GSE24585Up0.2104870140
GSE37065Up0.0097376535
GSE28863_A1Down-0.1300867519
GSE28863_A2Up0.1402494231
GSE28863_A3Up0.1661157121
GSE28863_A4Up0.1952891778
GSE48662Down-0.0743677794

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029920MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.