HCSGD entry for FBXO21
1. General information
| Official gene symbol | FBXO21 |
|---|---|
| Entrez ID | 23014 |
| Gene full name | F-box protein 21 |
| Other gene symbols | FBX21 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000151 | Ubiquitin ligase complex | NAS | cellular_component |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0004842 | Ubiquitin-protein ligase activity | NAS | molecular_function |
| GO:0006511 | Ubiquitin-dependent protein catabolic process | NAS | biological_process |
| GO:0016567 | Protein ubiquitination | NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9021843889 | 0.1609226853 | 0.9999902473 | 0.7740581140 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0925781604 |
| GSE13712_SHEAR | Down | -0.2970141972 |
| GSE13712_STATIC | Down | -0.1241461244 |
| GSE19018 | Up | 0.2561097385 |
| GSE19899_A1 | Down | -0.2731416949 |
| GSE19899_A2 | Down | -0.3432526489 |
| PubMed_21979375_A1 | Down | -0.5325095570 |
| PubMed_21979375_A2 | Down | -0.0786718999 |
| GSE35957 | Down | -0.0385750847 |
| GSE36640 | Down | -0.1239344728 |
| GSE54402 | Up | 0.0701173179 |
| GSE9593 | Up | 0.0040775063 |
| GSE43922 | Down | -0.3767894233 |
| GSE24585 | Up | 0.0933026914 |
| GSE37065 | Down | -0.0147808478 |
| GSE28863_A1 | Up | 0.4421228480 |
| GSE28863_A2 | Up | 0.4185050560 |
| GSE28863_A3 | Down | -0.4121321777 |
| GSE28863_A4 | Down | -0.0858346474 |
| GSE48662 | Down | -0.2059337502 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-340-5p | MIMAT0004692 | MIRT019578 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-96-5p | MIMAT0000095 | MIRT027913 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040547 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046784 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
