HCSGD entry for RAB21
1. General information
| Official gene symbol | RAB21 |
|---|---|
| Entrez ID | 23011 |
| Gene full name | RAB21, member RAS oncogene family |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0003924 | GTPase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005525 | GTP binding | IDA | molecular_function |
| GO:0005768 | Endosome | IDA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0006184 | GTP catabolic process | IDA | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | IEA | biological_process |
| GO:0008152 | Metabolic process | IDA | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0019003 | GDP binding | IDA | molecular_function |
| GO:0030659 | Cytoplasmic vesicle membrane | IEA | cellular_component |
| GO:0031901 | Early endosome membrane | IEA | cellular_component |
| GO:0032154 | Cleavage furrow | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2228496980 | 0.3025232324 | 0.9040289793 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0944339652 |
| GSE13712_SHEAR | Down | -0.1106836472 |
| GSE13712_STATIC | Down | -0.1351557708 |
| GSE19018 | Down | -0.1125661691 |
| GSE19899_A1 | Up | 0.0455317614 |
| GSE19899_A2 | Up | 0.0737990326 |
| PubMed_21979375_A1 | Down | -0.1547710398 |
| PubMed_21979375_A2 | Down | -0.1641827899 |
| GSE35957 | Up | 0.5947571768 |
| GSE36640 | Up | 0.5773963812 |
| GSE54402 | Down | -0.1593178813 |
| GSE9593 | Up | 0.1375147901 |
| GSE43922 | Up | 0.0236169340 |
| GSE24585 | Up | 0.0815206769 |
| GSE37065 | Up | 0.1786609787 |
| GSE28863_A1 | Up | 0.6836979332 |
| GSE28863_A2 | Up | 0.1051095923 |
| GSE28863_A3 | Down | -0.9920602299 |
| GSE28863_A4 | Down | -0.0270062710 |
| GSE48662 | Up | 0.0893830526 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT000811 | qRT-PCR | Functional MTI (Weak) | 18362358 |
| hsa-miR-15a-5p | MIMAT0000068 | MIRT000812 | qRT-PCR | Functional MTI (Weak) | 18362358 |
| hsa-miR-128-3p | MIMAT0000424 | MIRT022089 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028612 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036969 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7g-5p | MIMAT0000414 | MIRT046563 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-196a-5p | MIMAT0000226 | MIRT048278 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT050640 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-15a-5p | MIMAT0000068 | NA | hsa-miR-15a | 18362358 | |||
| hsa-miR-16-5p | MIMAT0000069 | NA | hsa-miR-16 | 18362358 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
