HCSGD entry for RIMS1

1. General information

Official gene symbolRIMS1
Entrez ID22999
Gene full nameregulating synaptic membrane exocytosis 1
Other gene symbolsCORD7 RAB3IP2 RIM RIM1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005083Small GTPase regulator activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0006461Protein complex assemblyIDAbiological_process
GO:0006886Intracellular protein transportIEAbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007269Neurotransmitter secretionTASbiological_process
GO:0007601Visual perceptionIEAbiological_process
GO:0014047Glutamate secretionTASbiological_process
GO:0016079Synaptic vesicle exocytosisTASbiological_process
GO:0017137Rab GTPase bindingIEAmolecular_function
GO:0017156Calcium ion-dependent exocytosisTASbiological_process
GO:0030054Cell junctionIEAcellular_component
GO:0042391Regulation of membrane potentialIEAbiological_process
GO:0042734Presynaptic membraneISS NAScellular_component
GO:0044325Ion channel bindingIEAmolecular_function
GO:0045055Regulated secretory pathwayNASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0046903SecretionNASbiological_process
GO:0048169Regulation of long-term neuronal synaptic plasticityIEAbiological_process
GO:0048791Calcium ion-dependent exocytosis of neurotransmitterIEAbiological_process
GO:0050790Regulation of catalytic activityTASbiological_process
GO:0050896Response to stimulusIEAbiological_process
GO:0061025Membrane fusionNASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.75236701490.01718222710.99999024730.2571082433

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0040548764
GSE13712_SHEARDown-0.0915508716
GSE13712_STATICDown-0.1475790290
GSE19018Down-0.0478586203
GSE19899_A1Up0.0109243544
GSE19899_A2Down-0.1005419509
PubMed_21979375_A1Down-0.3271026133
PubMed_21979375_A2Down-0.3091231636
GSE35957Up2.4371383126
GSE36640Up0.3213553981
GSE54402Down-0.2515023410
GSE9593Up0.1072922745
GSE43922Down-0.5879058348
GSE24585Up0.2791337656
GSE37065Down-0.1669802140
GSE28863_A1Down-1.0632044105
GSE28863_A2Down-0.3363826488
GSE28863_A3Down-1.7925489519
GSE28863_A4Down-0.0173425240
GSE48662Up0.1613145401

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.