HCSGD entry for ACIN1
1. General information
| Official gene symbol | ACIN1 |
|---|---|
| Entrez ID | 22985 |
| Gene full name | apoptotic chromatin condensation inducer 1 |
| Other gene symbols | ACINUS ACN fSAP152 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0003676 | Nucleic acid binding | IEA NAS | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006200 | ATP catabolic process | NAS | biological_process |
| GO:0006397 | MRNA processing | IEA | biological_process |
| GO:0006915 | Apoptotic process | TAS | biological_process |
| GO:0006921 | Cellular component disassembly involved in execution phase of apoptosis | TAS | biological_process |
| GO:0008380 | RNA splicing | IEA | biological_process |
| GO:0016607 | Nuclear speck | IDA | cellular_component |
| GO:0016887 | ATPase activity | NAS | molecular_function |
| GO:0019899 | Enzyme binding | NAS | molecular_function |
| GO:0030218 | Erythrocyte differentiation | IEP | biological_process |
| GO:0030263 | Apoptotic chromosome condensation | IDA | biological_process |
| GO:0035145 | Exon-exon junction complex | IDA | cellular_component |
| GO:0043065 | Positive regulation of apoptotic process | IDA | biological_process |
| GO:0045657 | Positive regulation of monocyte differentiation | IEP | biological_process |
| GO:0048025 | Negative regulation of mRNA splicing, via spliceosome | IDA | biological_process |
| GO:0061574 | ASAP complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4979800046 | 0.2569739030 | 0.9999902473 | 0.9719942537 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2263897602 |
| GSE13712_SHEAR | Up | 0.1212581729 |
| GSE13712_STATIC | Down | -0.1464604097 |
| GSE19018 | Down | -0.2491459632 |
| GSE19899_A1 | Down | -0.1810875453 |
| GSE19899_A2 | Down | -0.0732402012 |
| PubMed_21979375_A1 | Down | -0.3296098893 |
| PubMed_21979375_A2 | Down | -0.1796127123 |
| GSE35957 | Down | -0.4769616770 |
| GSE36640 | Down | -0.2770698359 |
| GSE54402 | Down | -0.0326167336 |
| GSE9593 | Down | -0.5133788154 |
| GSE43922 | Down | -0.0008877790 |
| GSE24585 | Down | -0.1457144076 |
| GSE37065 | Up | 0.0939657217 |
| GSE28863_A1 | Up | 0.4760947821 |
| GSE28863_A2 | Up | 0.3831591871 |
| GSE28863_A3 | Down | -0.0688648780 |
| GSE28863_A4 | Up | 0.0532563379 |
| GSE48662 | Up | 0.5889726970 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-340-5p | MIMAT0004692 | MIRT019549 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT027955 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-18a-5p | MIMAT0000072 | MIRT031335 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-1226-3p | MIMAT0005577 | MIRT036443 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-3p | MIMAT0004509 | MIRT038741 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043129 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106b-5p | MIMAT0000680 | MIRT044279 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT046954 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
