HCSGD entry for RAB18
1. General information
| Official gene symbol | RAB18 |
|---|---|
| Entrez ID | 22931 |
| Gene full name | RAB18, member RAS oncogene family |
| Other gene symbols | RAB18LI1 WARBM3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001654 | Eye development | ISS | biological_process |
| GO:0003924 | GTPase activity | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005622 | Intracellular | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006184 | GTP catabolic process | NAS | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | IEA NAS | biological_process |
| GO:0007420 | Brain development | ISS | biological_process |
| GO:0008152 | Metabolic process | NAS | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0019003 | GDP binding | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7549511113 | 0.4786111888 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1975266434 |
| GSE13712_SHEAR | Up | 0.1243795832 |
| GSE13712_STATIC | Down | -0.0301919151 |
| GSE19018 | Down | -0.1418991609 |
| GSE19899_A1 | Up | 0.0680614764 |
| GSE19899_A2 | Down | -0.1157944483 |
| PubMed_21979375_A1 | Down | -0.0584236618 |
| PubMed_21979375_A2 | Down | -0.0017822371 |
| GSE35957 | Up | 0.0562494580 |
| GSE36640 | Up | 0.1848622567 |
| GSE54402 | Up | 0.0544173999 |
| GSE9593 | Up | 0.0590729220 |
| GSE43922 | Down | -0.0390158040 |
| GSE24585 | Down | -0.0362202345 |
| GSE37065 | Up | 0.1290447703 |
| GSE28863_A1 | Down | -0.0548884727 |
| GSE28863_A2 | Up | 0.1438258596 |
| GSE28863_A3 | Down | -0.3212035397 |
| GSE28863_A4 | Down | -0.2280605950 |
| GSE48662 | Down | -0.2252561959 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-324-3p | MIMAT0000762 | MIRT042858 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30b-5p | MIMAT0000420 | MIRT046127 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047576 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047906 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-26a-5p | MIMAT0000082 | MIRT050093 | CLASH | Functional MTI (Weak) | 23622248 |
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