HCSGD entry for KIFAP3
1. General information
| Official gene symbol | KIFAP3 |
|---|---|
| Entrez ID | 22920 |
| Gene full name | kinesin-associated protein 3 |
| Other gene symbols | FLA3 KAP-1 KAP-3 KAP3 SMAP Smg-GDS dJ190I16.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000794 | Condensed nuclear chromosome | IDA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005783 | Endoplasmic reticulum | TAS | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005876 | Spindle microtubule | IDA | cellular_component |
| GO:0006461 | Protein complex assembly | TAS | biological_process |
| GO:0007017 | Microtubule-based process | IEA ISS | biological_process |
| GO:0007018 | Microtubule-based movement | TAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0008104 | Protein localization | IEA | biological_process |
| GO:0008285 | Negative regulation of cell proliferation | IEA | biological_process |
| GO:0016939 | Kinesin II complex | IDA IEA ISS | cellular_component |
| GO:0019886 | Antigen processing and presentation of exogenous peptide antigen via MHC class II | TAS | biological_process |
| GO:0019894 | Kinesin binding | IEA IPI | molecular_function |
| GO:0046587 | Positive regulation of calcium-dependent cell-cell adhesion | IEA | biological_process |
| GO:0072383 | Plus-end-directed vesicle transport along microtubule | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1568849930 | 0.2499468257 | 0.7861425662 | 0.9599956807 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2940563353 |
| GSE13712_SHEAR | Down | -0.5556228694 |
| GSE13712_STATIC | Down | -0.4119974477 |
| GSE19018 | Up | 0.3933866479 |
| GSE19899_A1 | Down | -0.2163270445 |
| GSE19899_A2 | Down | -0.5439594053 |
| PubMed_21979375_A1 | Down | -0.3984014950 |
| PubMed_21979375_A2 | Up | 0.0627621908 |
| GSE35957 | Down | -0.0120489592 |
| GSE36640 | Up | 0.2994289759 |
| GSE54402 | Down | -0.1240995769 |
| GSE9593 | Up | 0.1388310709 |
| GSE43922 | Down | -0.0710431419 |
| GSE24585 | Up | 0.6381037671 |
| GSE37065 | Up | 0.1693763752 |
| GSE28863_A1 | Up | 0.7022470431 |
| GSE28863_A2 | Up | 0.8425134491 |
| GSE28863_A3 | Down | -0.3606234269 |
| GSE28863_A4 | Down | -0.2679671782 |
| GSE48662 | Up | 0.0619870888 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-21-5p | MIMAT0000076 | MIRT030958 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-671-3p | MIMAT0004819 | MIRT037774 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-425-5p | MIMAT0003393 | MIRT039305 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
