HCSGD entry for NCBP2

1. General information

Official gene symbolNCBP2
Entrez ID22916
Gene full namenuclear cap binding protein subunit 2, 20kDa
Other gene symbolsCBC2 CBP20 NIP1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000166Nucleotide bindingIEAmolecular_function
GO:0000184Nuclear-transcribed mRNA catabolic process, nonsense-mediated decayIDA IMP TASbiological_process
GO:0000339RNA cap bindingIEA NASmolecular_function
GO:0000340RNA 7-methylguanosine cap bindingIDAmolecular_function
GO:0000387Spliceosomal snRNP assemblyTASbiological_process
GO:0000398MRNA splicing, via spliceosomeTASbiological_process
GO:0003723RNA bindingIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDA NAScellular_component
GO:0005654NucleoplasmIDA TAScellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005845MRNA cap binding complexIDAcellular_component
GO:0005846Nuclear cap binding complexIEAcellular_component
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0006368Transcription elongation from RNA polymerase II promoterTASbiological_process
GO:0006369Termination of RNA polymerase II transcriptionTASbiological_process
GO:00063707-methylguanosine mRNA cappingIDA TASbiological_process
GO:0006406MRNA export from nucleusTASbiological_process
GO:0006408SnRNA export from nucleusISS NASbiological_process
GO:0006446Regulation of translational initiationIDAbiological_process
GO:0008334Histone mRNA metabolic processTASbiological_process
GO:0008380RNA splicingISS TASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0016070RNA metabolic processTASbiological_process
GO:0016071MRNA metabolic processTASbiological_process
GO:0031047Gene silencing by RNAIEAbiological_process
GO:0031124MRNA 3'-end processingTASbiological_process
GO:0034660NcRNA metabolic processTASbiological_process
GO:0045292MRNA cis splicing, via spliceosomeIDA IEAbiological_process
GO:0046833Positive regulation of RNA export from nucleusISSbiological_process
GO:0050434Positive regulation of viral transcriptionTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.18997017970.78606383120.84789706781.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1345326725
GSE13712_SHEARUp0.3873752616
GSE13712_STATICUp0.2551452160
GSE19018Down-0.4020199199
GSE19899_A1Up0.3678036757
GSE19899_A2Up0.1266214529
PubMed_21979375_A1Up0.5179993978
PubMed_21979375_A2Down-0.3651918643
GSE35957Down-0.0165872590
GSE36640Down-0.1139518219
GSE54402Up0.3011331913
GSE9593Down-0.0687419965
GSE43922Up0.0759400477
GSE24585Down-0.1479786467
GSE37065Down-0.0593053215
GSE28863_A1Up0.0070616473
GSE28863_A2Up0.4013532861
GSE28863_A3Up0.0340420829
GSE28863_A4Down-0.0502478231
GSE48662Up0.0485684259

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-34a-5pMIMAT0000255MIRT025377SequencingFunctional MTI (Weak)20371350
hsa-miR-192-5pMIMAT0000222MIRT026313SequencingFunctional MTI (Weak)20371350
hsa-miR-24-3pMIMAT0000080MIRT030403MicroarrayFunctional MTI (Weak)19748357
hsa-miR-10a-3pMIMAT0004555MIRT038675CLASHFunctional MTI (Weak)23622248
hsa-miR-19b-3pMIMAT0000074MIRT050630CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.