HCSGD entry for FOXG1
1. General information
| Official gene symbol | FOXG1 |
|---|---|
| Entrez ID | 2290 |
| Gene full name | forkhead box G1 |
| Other gene symbols | BF1 BF2 FHKL3 FKH2 FKHL1 FKHL2 FKHL3 FKHL4 FOXG1A FOXG1B FOXG1C HBF-1 HBF-2 HBF-3 HBF-G2 HBF2 HFK1 HFK2 HFK3 KHL2 QIN |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002052 | Positive regulation of neuroblast proliferation | IEA | biological_process |
| GO:0003677 | DNA binding | TAS | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007346 | Regulation of mitotic cell cycle | IEA | biological_process |
| GO:0007420 | Brain development | TAS | biological_process |
| GO:0007568 | Aging | IEA | biological_process |
| GO:0009953 | Dorsal/ventral pattern formation | IEA | biological_process |
| GO:0016199 | Axon midline choice point recognition | IEA | biological_process |
| GO:0021852 | Pyramidal neuron migration | IEA | biological_process |
| GO:0042472 | Inner ear morphogenesis | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0045665 | Negative regulation of neuron differentiation | IEA | biological_process |
| GO:0045787 | Positive regulation of cell cycle | IEA | biological_process |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0048664 | Neuron fate determination | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1035355800 | 0.9573090042 | 0.6690669858 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1458593622 |
| GSE13712_SHEAR | Down | -0.0593911569 |
| GSE13712_STATIC | Up | 0.0318168205 |
| GSE19018 | Down | -0.1280459120 |
| GSE19899_A1 | Down | -0.0168209269 |
| GSE19899_A2 | Up | 0.3684126616 |
| PubMed_21979375_A1 | Up | 0.3233424083 |
| PubMed_21979375_A2 | Up | 0.1714531511 |
| GSE35957 | Down | -0.0781789790 |
| GSE36640 | Up | 0.9429452276 |
| GSE54402 | Up | 0.7182008171 |
| GSE9593 | Down | -0.0292273754 |
| GSE43922 | Up | 0.1098364492 |
| GSE24585 | Up | 0.6179972784 |
| GSE37065 | Down | -0.1695540237 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.1049338083 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-590-3p | MIMAT0004801 | MIRT016200 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029405 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 22668500 | In RT-qPCR experiments, the levels of pyruvate kinase M2 mRNA dropped, whereas the levels of ATP synthase (beta-F1) mRNA increased |
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