HCSGD entry for ARHGEF15

1. General information

Official gene symbolARHGEF15
Entrez ID22899
Gene full nameRho guanine nucleotide exchange factor (GEF) 15
Other gene symbolsARGEF15 E5 Ephexin5 Vsm-RhoGEF
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005089Rho guanyl-nucleotide exchange factor activityIDA IEA ISSmolecular_function
GO:0005096GTPase activator activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0030425DendriteIEA ISScellular_component
GO:0032318Regulation of Ras GTPase activityIDA ISSbiological_process
GO:0032319Regulation of Rho GTPase activityIDA ISSbiological_process
GO:0043087Regulation of GTPase activityIDA ISSbiological_process
GO:0050790Regulation of catalytic activityIDAbiological_process
GO:0061299Retina vasculature morphogenesis in camera-type eyeIEAbiological_process
GO:2000297Negative regulation of synapse maturationIEA ISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.33606666540.88949928950.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0918757294
GSE13712_SHEARDown-0.1620283168
GSE13712_STATICDown-0.1901394710
GSE19018Down-0.0152362838
GSE19899_A1Up0.0106260788
GSE19899_A2Up0.2259451888
PubMed_21979375_A1Down-0.2212253867
PubMed_21979375_A2Up0.0836694198
GSE35957Up0.1320819487
GSE36640Up0.0706376930
GSE54402Down-0.0514966968
GSE9593Up0.1490978919
GSE43922Up0.0503291428
GSE24585Up0.1463192498
GSE37065Down-0.0839126487
GSE28863_A1Down-0.0638513588
GSE28863_A2Down-0.0572807311
GSE28863_A3Up0.2953288978
GSE28863_A4Up0.0963906021
GSE48662Up0.7624935770

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.