HCSGD entry for DENND3
1. General information
| Official gene symbol | DENND3 |
|---|---|
| Entrez ID | 22898 |
| Gene full name | DENN/MADD domain containing 3 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0008333 | Endosome to lysosome transport | IEA ISS | biological_process |
| GO:0017112 | Rab guanyl-nucleotide exchange factor activity | IDA IEA | molecular_function |
| GO:0032313 | Regulation of Rab GTPase activity | IDA | biological_process |
| GO:0032318 | Regulation of Ras GTPase activity | IDA | biological_process |
| GO:0043087 | Regulation of GTPase activity | IDA | biological_process |
| GO:0044257 | Cellular protein catabolic process | IEA ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1568939972 | 0.0941797538 | 0.7861425662 | 0.5846837303 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0508736766 |
| GSE13712_SHEAR | Up | 0.0090285518 |
| GSE13712_STATIC | Up | 0.4321639264 |
| GSE19018 | Up | 0.2709147247 |
| GSE19899_A1 | Down | -0.6229959367 |
| GSE19899_A2 | Up | 0.1576145948 |
| PubMed_21979375_A1 | Down | -1.1814107618 |
| PubMed_21979375_A2 | Down | -0.4556703536 |
| GSE35957 | Up | 0.2614009573 |
| GSE36640 | Up | 0.5979495886 |
| GSE54402 | Down | -0.3739327985 |
| GSE9593 | Up | 0.0584947956 |
| GSE43922 | Down | -1.3930002262 |
| GSE24585 | Up | 0.4695661022 |
| GSE37065 | Up | 0.4127101752 |
| GSE28863_A1 | Up | 0.0636016107 |
| GSE28863_A2 | Up | 0.5199262953 |
| GSE28863_A3 | Down | -0.0134888768 |
| GSE28863_A4 | Down | -0.0170373736 |
| GSE48662 | Down | -0.2786087525 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT019167 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
