HCSGD entry for ZBTB1
1. General information
| Official gene symbol | ZBTB1 |
|---|---|
| Entrez ID | 22890 |
| Gene full name | zinc finger and BTB domain containing 1 |
| Other gene symbols | ZNF909 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0002711 | Positive regulation of T cell mediated immunity | ISS | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | IDA | cellular_component |
| GO:0016604 | Nuclear body | IDA | cellular_component |
| GO:0030183 | B cell differentiation | IEA | biological_process |
| GO:0032825 | Positive regulation of natural killer cell differentiation | ISS | biological_process |
| GO:0033077 | T cell differentiation in thymus | IEA | biological_process |
| GO:0042789 | MRNA transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0042803 | Protein homodimerization activity | IDA | molecular_function |
| GO:0045087 | Innate immune response | IEA | biological_process |
| GO:0045582 | Positive regulation of T cell differentiation | ISS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0046982 | Protein heterodimerization activity | IDA | molecular_function |
| GO:0048538 | Thymus development | ISS | biological_process |
| GO:0051260 | Protein homooligomerization | IDA | biological_process |
| GO:2000176 | Positive regulation of pro-T cell differentiation | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0621219065 | 0.2967884047 | 0.5391219183 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.5061220294 |
| GSE13712_SHEAR | Up | 0.1250047810 |
| GSE13712_STATIC | Up | 0.0480716245 |
| GSE19018 | Up | 0.0481091852 |
| GSE19899_A1 | Up | 0.0605691640 |
| GSE19899_A2 | Up | 0.4249258110 |
| PubMed_21979375_A1 | Up | 0.9588461734 |
| PubMed_21979375_A2 | Up | 0.7359389090 |
| GSE35957 | Down | -0.2155275743 |
| GSE36640 | Up | 0.5294264840 |
| GSE54402 | Up | 0.2749227624 |
| GSE9593 | Down | -0.5556902071 |
| GSE43922 | Up | 0.2508625524 |
| GSE24585 | Up | 0.8425257713 |
| GSE37065 | Up | 0.3055775782 |
| GSE28863_A1 | Up | 0.0722847151 |
| GSE28863_A2 | Down | -0.2916022240 |
| GSE28863_A3 | Down | -0.7916079686 |
| GSE28863_A4 | Down | -0.2461105020 |
| GSE48662 | Down | -0.0854938317 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017131 | Microarray | Functional MTI (Weak) | 18185580 |
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