HCSGD entry for ZBTB1


1. General information

Official gene symbolZBTB1
Entrez ID22890
Gene full namezinc finger and BTB domain containing 1
Other gene symbolsZNF909
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0002711Positive regulation of T cell mediated immunityISSbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmIDAcellular_component
GO:0016604Nuclear bodyIDAcellular_component
GO:0030183B cell differentiationIEAbiological_process
GO:0032825Positive regulation of natural killer cell differentiationISSbiological_process
GO:0033077T cell differentiation in thymusIEAbiological_process
GO:0042789MRNA transcription from RNA polymerase II promoterIDAbiological_process
GO:0042803Protein homodimerization activityIDAmolecular_function
GO:0045087Innate immune responseIEAbiological_process
GO:0045582Positive regulation of T cell differentiationISSbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0046982Protein heterodimerization activityIDAmolecular_function
GO:0048538Thymus developmentISSbiological_process
GO:0051260Protein homooligomerizationIDAbiological_process
GO:2000176Positive regulation of pro-T cell differentiationISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.06212190650.29678840470.53912191831.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.5061220294
GSE13712_SHEARUp0.1250047810
GSE13712_STATICUp0.0480716245
GSE19018Up0.0481091852
GSE19899_A1Up0.0605691640
GSE19899_A2Up0.4249258110
PubMed_21979375_A1Up0.9588461734
PubMed_21979375_A2Up0.7359389090
GSE35957Down-0.2155275743
GSE36640Up0.5294264840
GSE54402Up0.2749227624
GSE9593Down-0.5556902071
GSE43922Up0.2508625524
GSE24585Up0.8425257713
GSE37065Up0.3055775782
GSE28863_A1Up0.0722847151
GSE28863_A2Down-0.2916022240
GSE28863_A3Down-0.7916079686
GSE28863_A4Down-0.2461105020
GSE48662Down-0.0854938317

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017131MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.