HCSGD entry for ZHX2

1. General information

Official gene symbolZHX2
Entrez ID22882
Gene full namezinc fingers and homeoboxes 2
Other gene symbolsAFR1 RAF
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIDA IEAbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityIDAmolecular_function
GO:0003714Transcription corepressor activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006402MRNA catabolic processIEAbiological_process
GO:0035019Somatic stem cell maintenanceIEAbiological_process
GO:0042803Protein homodimerization activityIDAmolecular_function
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045665Negative regulation of neuron differentiationIEAbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedIDAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0046982Protein heterodimerization activityIDAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.03268503100.94070060410.41683643411.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1897842911
GSE13712_SHEARUp0.0223580017
GSE13712_STATICDown-0.0381429474
GSE19018Up0.8986001570
GSE19899_A1Down-0.0708849393
GSE19899_A2Up0.4250795725
PubMed_21979375_A1Up0.4993556762
PubMed_21979375_A2Up0.9353897657
GSE35957Up0.0769906548
GSE36640Up0.6311039826
GSE54402Up0.1024869436
GSE9593Up0.0497401704
GSE43922Up0.0512923322
GSE24585Down-0.0664489816
GSE37065Up0.2298979797
GSE28863_A1Up0.1764860624
GSE28863_A2Down-0.0040371126
GSE28863_A3Down-0.2094050199
GSE28863_A4Up0.0202680313
GSE48662Up0.2823386465

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.