HCSGD entry for LMTK2
1. General information
| Official gene symbol | LMTK2 |
|---|---|
| Entrez ID | 22853 |
| Gene full name | lemur tyrosine kinase 2 |
| Other gene symbols | AATYK2 BREK KPI-2 KPI2 LMR2 cprk |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001881 | Receptor recycling | IMP | biological_process |
| GO:0004674 | Protein serine/threonine kinase activity | IDA | molecular_function |
| GO:0004713 | Protein tyrosine kinase activity | IEA | molecular_function |
| GO:0004864 | Protein phosphatase inhibitor activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | NAS | molecular_function |
| GO:0005769 | Early endosome | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0006468 | Protein phosphorylation | IDA | biological_process |
| GO:0016021 | Integral component of membrane | IDA | cellular_component |
| GO:0018105 | Peptidyl-serine phosphorylation | IDA | biological_process |
| GO:0018107 | Peptidyl-threonine phosphorylation | IDA | biological_process |
| GO:0032456 | Endocytic recycling | IMP | biological_process |
| GO:0033572 | Transferrin transport | IMP | biological_process |
| GO:0043086 | Negative regulation of catalytic activity | IDA | biological_process |
| GO:0045022 | Early endosome to late endosome transport | IMP | biological_process |
| GO:0046777 | Protein autophosphorylation | IDA | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IDA | cellular_component |
| GO:0050790 | Regulation of catalytic activity | IDA | biological_process |
| GO:0055037 | Recycling endosome | IDA | cellular_component |
| GO:0070853 | Myosin VI binding | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0312929030 | 0.9909674746 | 0.4099809312 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0031448271 |
| GSE13712_SHEAR | Up | 0.1030861136 |
| GSE13712_STATIC | Up | 0.2580590390 |
| GSE19018 | Down | -0.0863276236 |
| GSE19899_A1 | Up | 0.1321126957 |
| GSE19899_A2 | Up | 0.0714081680 |
| PubMed_21979375_A1 | Up | 0.6509537366 |
| PubMed_21979375_A2 | Up | 0.2861777642 |
| GSE35957 | Up | 0.0296881004 |
| GSE36640 | Down | -0.0104707147 |
| GSE54402 | Up | 0.1975656402 |
| GSE9593 | Up | 0.1297086798 |
| GSE43922 | Up | 0.6085502200 |
| GSE24585 | Up | 0.2105334431 |
| GSE37065 | Up | 0.2218735667 |
| GSE28863_A1 | Up | 0.6206573812 |
| GSE28863_A2 | Up | 0.6549766870 |
| GSE28863_A3 | Up | 0.2772989121 |
| GSE28863_A4 | Down | -0.1241313547 |
| GSE48662 | Up | 0.2016482290 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017926 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040175 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
