HCSGD entry for AAK1
1. General information
| Official gene symbol | AAK1 |
|---|---|
| Entrez ID | 22848 |
| Gene full name | AP2 associated kinase 1 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004674 | Protein serine/threonine kinase activity | IEA ISS | molecular_function |
| GO:0005112 | Notch binding | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005905 | Coated pit | IEA | cellular_component |
| GO:0006468 | Protein phosphorylation | IDA | biological_process |
| GO:0006897 | Endocytosis | IEA | biological_process |
| GO:0019897 | Extrinsic component of plasma membrane | ISS | cellular_component |
| GO:0030136 | Clathrin-coated vesicle | ISS | cellular_component |
| GO:0031252 | Cell leading edge | ISS | cellular_component |
| GO:0032880 | Regulation of protein localization | IDA | biological_process |
| GO:0035612 | AP-2 adaptor complex binding | IDA | molecular_function |
| GO:0043195 | Terminal bouton | ISS | cellular_component |
| GO:0045747 | Positive regulation of Notch signaling pathway | IDA | biological_process |
| GO:0046777 | Protein autophosphorylation | ISS | biological_process |
| GO:0050821 | Protein stabilization | IDA | biological_process |
| GO:2000369 | Regulation of clathrin-mediated endocytosis | IDA IMP | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9319305725 | 0.2503261274 | 0.9999902473 | 0.9606114594 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0753709791 |
| GSE13712_SHEAR | Up | 0.0171360423 |
| GSE13712_STATIC | Down | -0.0733230437 |
| GSE19018 | Down | -0.0442084785 |
| GSE19899_A1 | Down | -0.0958960683 |
| GSE19899_A2 | Up | 0.0134052400 |
| PubMed_21979375_A1 | Down | -0.6799027748 |
| PubMed_21979375_A2 | Down | -0.0232103946 |
| GSE35957 | Up | 0.0352545658 |
| GSE36640 | Down | -0.0198845848 |
| GSE54402 | Up | 0.0013970241 |
| GSE9593 | Up | 0.1202576783 |
| GSE43922 | Down | -0.1902733749 |
| GSE24585 | Down | -0.2473789354 |
| GSE37065 | Up | 0.0384482210 |
| GSE28863_A1 | Up | 0.2129704069 |
| GSE28863_A2 | Up | 0.0947594938 |
| GSE28863_A3 | Down | -0.2990981490 |
| GSE28863_A4 | Down | -0.3942596854 |
| GSE48662 | Up | 0.1208369293 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
