HCSGD entry for PPM1E
1. General information
| Official gene symbol | PPM1E |
|---|---|
| Entrez ID | 22843 |
| Gene full name | protein phosphatase, Mg2+/Mn2+ dependent, 1E |
| Other gene symbols | CaMKP-N POPX1 PP2CH caMKN |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004722 | Protein serine/threonine phosphatase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0006469 | Negative regulation of protein kinase activity | IDA | biological_process |
| GO:0035690 | Cellular response to drug | IDA | biological_process |
| GO:0035970 | Peptidyl-threonine dephosphorylation | IDA | biological_process |
| GO:0043234 | Protein complex | IDA | cellular_component |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0051496 | Positive regulation of stress fiber assembly | IDA | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5082872231 | 0.8129076403 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2309785958 |
| GSE13712_SHEAR | Up | 0.1293786279 |
| GSE13712_STATIC | Up | 0.0191836500 |
| GSE19018 | Up | 0.1294049214 |
| GSE19899_A1 | Up | 0.1437286184 |
| GSE19899_A2 | Down | -0.0927968991 |
| PubMed_21979375_A1 | Down | -0.1951054063 |
| PubMed_21979375_A2 | Up | 0.0384277296 |
| GSE35957 | Down | -0.2102803620 |
| GSE36640 | Down | -0.0656593214 |
| GSE54402 | Down | -0.1413993723 |
| GSE9593 | Down | -0.0011230787 |
| GSE43922 | Up | 0.1700995636 |
| GSE24585 | Up | 0.4267165045 |
| GSE37065 | Down | -0.1239607077 |
| GSE28863_A1 | Down | -0.0616090574 |
| GSE28863_A2 | Up | 0.0216208464 |
| GSE28863_A3 | Up | 0.1799849099 |
| GSE28863_A4 | Up | 0.0215688003 |
| GSE48662 | Down | -0.0280269408 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018391 | Microarray | Functional MTI (Weak) | 18185580 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
