HCSGD entry for PUF60
1. General information
| Official gene symbol | PUF60 |
|---|---|
| Entrez ID | 22827 |
| Gene full name | poly-U binding splicing factor 60KDa |
| Other gene symbols | FIR RoBPI SIAHBP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0006397 | MRNA processing | IEA | biological_process |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0008380 | RNA splicing | IEA | biological_process |
| GO:0019907 | Cyclin-dependent protein kinase activating kinase holoenzyme complex | IDA | cellular_component |
| GO:0030529 | Ribonucleoprotein complex | IEA | cellular_component |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2310321036 | 0.5765808062 | 0.9146752556 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1663932313 |
| GSE13712_SHEAR | Up | 0.0732860002 |
| GSE13712_STATIC | Up | 0.0416337447 |
| GSE19018 | Down | -0.4074367771 |
| GSE19899_A1 | Up | 0.2174200134 |
| GSE19899_A2 | Up | 0.6882556672 |
| PubMed_21979375_A1 | Up | 0.9019047344 |
| PubMed_21979375_A2 | Up | 0.5202990260 |
| GSE35957 | Down | -0.3301912896 |
| GSE36640 | Down | -0.4682845849 |
| GSE54402 | Up | 0.4816471579 |
| GSE9593 | Down | -0.3777227473 |
| GSE43922 | Up | 0.1933992846 |
| GSE24585 | Down | -0.2221191422 |
| GSE37065 | Down | -0.2991225796 |
| GSE28863_A1 | Down | -0.0328345873 |
| GSE28863_A2 | Down | -0.0024350009 |
| GSE28863_A3 | Up | 0.0398466097 |
| GSE28863_A4 | Up | 0.0556326545 |
| GSE48662 | Down | -0.1047035171 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-93-3p | MIMAT0004509 | MIRT038851 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT042259 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
