HCSGD entry for ATF5
1. General information
| Official gene symbol | ATF5 |
|---|---|
| Entrez ID | 22809 |
| Gene full name | activating transcription factor 5 |
| Other gene symbols | ATFX HMFN0395 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0003714 | Transcription corepressor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0005667 | Transcription factor complex | IEA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0009791 | Post-embryonic development | IEA | biological_process |
| GO:0021891 | Olfactory bulb interneuron development | IEA | biological_process |
| GO:0031072 | Heat shock protein binding | IEA | molecular_function |
| GO:0035264 | Multicellular organism growth | IEA | biological_process |
| GO:0043066 | Negative regulation of apoptotic process | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0048712 | Negative regulation of astrocyte differentiation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0694120018 | 0.9382185213 | 0.5635389574 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0372784728 |
| GSE13712_SHEAR | Up | 0.2625777484 |
| GSE13712_STATIC | Up | 0.1616648958 |
| GSE19018 | Up | 0.0019999670 |
| GSE19899_A1 | Down | -0.0851120491 |
| GSE19899_A2 | Up | 0.3218086822 |
| PubMed_21979375_A1 | Up | 0.4998820264 |
| PubMed_21979375_A2 | Up | 0.2210469145 |
| GSE35957 | Down | -0.0415040579 |
| GSE36640 | Up | 0.2977925043 |
| GSE54402 | Up | 0.1266007025 |
| GSE9593 | Up | 0.0303696946 |
| GSE43922 | Up | 0.0350691205 |
| GSE24585 | Up | 0.4298315391 |
| GSE37065 | Down | -0.2767574786 |
| GSE28863_A1 | Down | -0.0465039886 |
| GSE28863_A2 | Down | -0.0479571272 |
| GSE28863_A3 | Up | 0.7685345157 |
| GSE28863_A4 | Up | 0.0091850453 |
| GSE48662 | Up | 0.4021988883 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-7-5p | MIMAT0000252 | MIRT025724 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046831 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
