HCSGD entry for MRAS
1. General information
| Official gene symbol | MRAS |
|---|---|
| Entrez ID | 22808 |
| Gene full name | muscle RAS oncogene homolog |
| Other gene symbols | M-RAs R-RAS3 RRAS3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003924 | GTPase activity | IEA | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0007264 | Small GTPase mediated signal transduction | IEA | biological_process |
| GO:0007265 | Ras protein signal transduction | TAS | biological_process |
| GO:0007275 | Multicellular organismal development | TAS | biological_process |
| GO:0007517 | Muscle organ development | TAS | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0030036 | Actin cytoskeleton organization | TAS | biological_process |
| GO:0030742 | GTP-dependent protein binding | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8289399035 | 0.0307577182 | 0.9999902473 | 0.3305732544 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1328040845 |
| GSE13712_SHEAR | Down | -1.4393461762 |
| GSE13712_STATIC | Down | -0.4124680211 |
| GSE19018 | Down | -0.7702392793 |
| GSE19899_A1 | Down | -0.3409166981 |
| GSE19899_A2 | Down | -0.3630056961 |
| PubMed_21979375_A1 | Up | 0.1343250281 |
| PubMed_21979375_A2 | Up | 0.2939247678 |
| GSE35957 | Up | 0.0300545884 |
| GSE36640 | Up | 0.7582079586 |
| GSE54402 | Down | -0.0095685524 |
| GSE9593 | Up | 0.0298029048 |
| GSE43922 | Down | -0.2865342771 |
| GSE24585 | Up | 0.6138945524 |
| GSE37065 | Down | -0.1003131311 |
| GSE28863_A1 | Down | -0.1307890327 |
| GSE28863_A2 | Up | 0.0291478440 |
| GSE28863_A3 | Down | -0.5160232540 |
| GSE28863_A4 | Down | -0.2149299388 |
| GSE48662 | Up | 0.0853693360 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-652-3p | MIMAT0003322 | MIRT039529 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
