HCSGD entry for IKZF2
1. General information
| Official gene symbol | IKZF2 |
|---|---|
| Entrez ID | 22807 |
| Gene full name | IKAROS family zinc finger 2 (Helios) |
| Other gene symbols | ANF1A2 HELIOS ZNF1A2 ZNFN1A2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0042803 | Protein homodimerization activity | IEA | molecular_function |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0046982 | Protein heterodimerization activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2851492155 | 0.1714028076 | 0.9842069761 | 0.8013247514 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0484058553 |
| GSE13712_SHEAR | Down | -0.2720309603 |
| GSE13712_STATIC | Down | -0.0489048866 |
| GSE19018 | Up | 0.2068497975 |
| GSE19899_A1 | Down | -0.0181752493 |
| GSE19899_A2 | Down | -0.2731449067 |
| PubMed_21979375_A1 | Down | -0.6269576703 |
| PubMed_21979375_A2 | Down | -0.2259828150 |
| GSE35957 | Down | -0.1284336144 |
| GSE36640 | Up | 0.2871121064 |
| GSE54402 | Up | 0.3783026539 |
| GSE9593 | Down | -0.0737450815 |
| GSE43922 | Down | -0.4612568372 |
| GSE24585 | Up | 1.9813943731 |
| GSE37065 | Up | 0.5796524457 |
| GSE28863_A1 | Down | -0.1029706355 |
| GSE28863_A2 | Down | -0.1085876723 |
| GSE28863_A3 | Down | -0.2797577779 |
| GSE28863_A4 | Down | -0.3446239009 |
| GSE48662 | Up | 0.1508879525 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-130b-5p | MIMAT0004680 | MIRT038326 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
