HCSGD entry for RRAS2
1. General information
| Official gene symbol | RRAS2 |
|---|---|
| Entrez ID | 22800 |
| Gene full name | related RAS viral (r-ras) oncogene homolog 2 |
| Other gene symbols | TC21 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003924 | GTPase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | NAS | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0007264 | Small GTPase mediated signal transduction | IEA | biological_process |
| GO:0007265 | Ras protein signal transduction | IEA | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0030335 | Positive regulation of cell migration | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1686348391 | 0.0370576346 | 0.8090845060 | 0.3629752788 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2103813396 |
| GSE13712_SHEAR | Up | 0.4911430584 |
| GSE13712_STATIC | Up | 0.2405025277 |
| GSE19018 | Up | 0.7501367639 |
| GSE19899_A1 | Down | -1.5719587033 |
| GSE19899_A2 | Down | -0.7387822323 |
| PubMed_21979375_A1 | Down | -0.6427560561 |
| PubMed_21979375_A2 | Down | -1.4670609179 |
| GSE35957 | Up | 0.9787644186 |
| GSE36640 | Up | 0.1960838567 |
| GSE54402 | Down | -1.2463073632 |
| GSE9593 | Up | 0.7278276190 |
| GSE43922 | Down | -0.6823567740 |
| GSE24585 | Up | 0.0692176085 |
| GSE37065 | Down | -0.1061678752 |
| GSE28863_A1 | Down | -0.2022085364 |
| GSE28863_A2 | Up | 0.0841659513 |
| GSE28863_A3 | Up | 0.1743461524 |
| GSE28863_A4 | Down | -0.0080166257 |
| GSE48662 | Up | 0.3664772890 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022861 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025875 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT028141 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029816 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031260 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
