HCSGD entry for ALDOA
1. General information
| Official gene symbol | ALDOA |
|---|---|
| Entrez ID | 226 |
| Gene full name | aldolase A, fructose-bisphosphate |
| Other gene symbols | ALDA GSD12 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002576 | Platelet degranulation | TAS | biological_process |
| GO:0003779 | Actin binding | TAS | molecular_function |
| GO:0004332 | Fructose-bisphosphate aldolase activity | IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0006000 | Fructose metabolic process | IMP | biological_process |
| GO:0006006 | Glucose metabolic process | TAS | biological_process |
| GO:0006094 | Gluconeogenesis | TAS | biological_process |
| GO:0006096 | Glycolysis | IEA IMP TAS | biological_process |
| GO:0006754 | ATP biosynthetic process | IMP | biological_process |
| GO:0006941 | Striated muscle contraction | IMP | biological_process |
| GO:0007015 | Actin filament organization | TAS | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0008092 | Cytoskeletal protein binding | IDA | molecular_function |
| GO:0008360 | Regulation of cell shape | IDA | biological_process |
| GO:0015629 | Actin cytoskeleton | IDA | cellular_component |
| GO:0015631 | Tubulin binding | TAS | molecular_function |
| GO:0030168 | Platelet activation | TAS | biological_process |
| GO:0030388 | Fructose 1,6-bisphosphate metabolic process | IDA | biological_process |
| GO:0031093 | Platelet alpha granule lumen | TAS | cellular_component |
| GO:0031674 | I band | TAS | cellular_component |
| GO:0042802 | Identical protein binding | TAS | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046716 | Muscle cell cellular homeostasis | IMP | biological_process |
| GO:0051289 | Protein homotetramerization | ISS | biological_process |
| GO:0070061 | Fructose binding | IDA | molecular_function |
| GO:0070062 | Extracellular vesicular exosome | IDA | cellular_component |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2157274116 | 0.8035039930 | 0.8941770430 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1757320528 |
| GSE13712_SHEAR | Up | 0.3495441408 |
| GSE13712_STATIC | Up | 0.2472520459 |
| GSE19018 | Up | 0.7843372716 |
| GSE19899_A1 | Down | -0.0371853545 |
| GSE19899_A2 | Up | 0.2553951296 |
| PubMed_21979375_A1 | Up | 0.9883783660 |
| PubMed_21979375_A2 | Up | 0.3023904250 |
| GSE35957 | Down | -0.1077772521 |
| GSE36640 | Down | -0.4160600240 |
| GSE54402 | Up | 0.1064901439 |
| GSE9593 | Down | -0.0275936181 |
| GSE43922 | Down | -0.0263466077 |
| GSE24585 | Down | -0.1129505497 |
| GSE37065 | Down | -0.1507116727 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.2430761756 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| 1,6-Fructose Diphosphate (Linear Form) | DB02512 | EXPT00120 |
| 1,3-Dihydroxyacetonephosphate | DB04326 | EXPT00026 |
| 1,6-DI-O-PHOSPHONO-D-MANNITOL | DB04733 | - |
| N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDE | DB08240 | - |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-122-5p | MIMAT0000421 | MIRT003085 | Luciferase reporter assay//qRT-PCR | Functional MTI | 19296470 |
| hsa-miR-122-5p | MIMAT0000421 | MIRT003085 | Northern blot | Functional MTI (Weak) | 18073344 |
| hsa-miR-1301-3p | MIMAT0005797 | MIRT036065 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040003 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040648 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-196b-5p | MIMAT0001080 | MIRT042671 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT042956 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043086 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23b-3p | MIMAT0000418 | MIRT046363 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-1260b | MIMAT0015041 | MIRT052739 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
