HCSGD entry for FGF10

1. General information

Official gene symbolFGF10
Entrez ID2255
Gene full namefibroblast growth factor 10
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000187Activation of MAPK activityIDAbiological_process
GO:0001525AngiogenesisIEAbiological_process
GO:0001656Metanephros developmentIEPbiological_process
GO:0001759Organ inductionIEAbiological_process
GO:0001823Mesonephros developmentIEPbiological_process
GO:0001974Blood vessel remodelingIEAbiological_process
GO:0003338Metanephros morphogenesisIEAbiological_process
GO:0005104Fibroblast growth factor receptor bindingIDAmolecular_function
GO:0005111Type 2 fibroblast growth factor receptor bindingIPImolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005615Extracellular spaceIDA IEAcellular_component
GO:0005634NucleusIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0007173Epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0007368Determination of left/right symmetryIEAbiological_process
GO:0007431Salivary gland developmentIMPbiological_process
GO:0008083Growth factor activityIDAmolecular_function
GO:0008201Heparin bindingIDAmolecular_function
GO:0008285Negative regulation of cell proliferationIEAbiological_process
GO:0008286Insulin receptor signaling pathwayTASbiological_process
GO:0008543Fibroblast growth factor receptor signaling pathwayTASbiological_process
GO:0008589Regulation of smoothened signaling pathwayIEAbiological_process
GO:0009880Embryonic pattern specificationIEAbiological_process
GO:0009986Cell surfaceIDA NAScellular_component
GO:0010631Epithelial cell migrationIEAbiological_process
GO:0010634Positive regulation of epithelial cell migrationIDA IEAbiological_process
GO:0010838Positive regulation of keratinocyte proliferationIDAbiological_process
GO:0021983Pituitary gland developmentIEAbiological_process
GO:0030538Embryonic genitalia morphogenesisIEAbiological_process
GO:0030878Thyroid gland developmentIEAbiological_process
GO:0030916Otic vesicle formationIEAbiological_process
GO:0030949Positive regulation of vascular endothelial growth factor receptor signaling pathwayIEAbiological_process
GO:0031012Extracellular matrixIDAcellular_component
GO:0031016Pancreas developmentIEAbiological_process
GO:0031069Hair follicle morphogenesisIEAbiological_process
GO:0031076Embryonic camera-type eye developmentIEAbiological_process
GO:0031532Actin cytoskeleton reorganizationIDAbiological_process
GO:0031659Positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycleIDAbiological_process
GO:0032355Response to estradiolIEAbiological_process
GO:0032496Response to lipopolysaccharideIEAbiological_process
GO:0032781Positive regulation of ATPase activityIDAbiological_process
GO:0032808Lacrimal gland developmentIEA IMPbiological_process
GO:0032925Regulation of activin receptor signaling pathwayIEAbiological_process
GO:0034394Protein localization to cell surfaceIDAbiological_process
GO:0035019Somatic stem cell maintenanceIEAbiological_process
GO:0035265Organ growthIEAbiological_process
GO:0038095Fc-epsilon receptor signaling pathwayTASbiological_process
GO:0042056Chemoattractant activityIDA IEAmolecular_function
GO:0042060Wound healingIDAbiological_process
GO:0042246Tissue regenerationIEAbiological_process
GO:0042475Odontogenesis of dentin-containing toothIEAbiological_process
GO:0042693Muscle cell fate commitmentIEAbiological_process
GO:0043410Positive regulation of MAPK cascadeIDAbiological_process
GO:0043616Keratinocyte proliferationIEAbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0045739Positive regulation of DNA repairIDAbiological_process
GO:0045740Positive regulation of DNA replicationIMPbiological_process
GO:0045747Positive regulation of Notch signaling pathwayIEAbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedIDAbiological_process
GO:0045931Positive regulation of mitotic cell cycleIEAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0046579Positive regulation of Ras protein signal transductionIDAbiological_process
GO:0046877Regulation of saliva secretionIMPbiological_process
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0048015Phosphatidylinositol-mediated signalingTASbiological_process
GO:0048146Positive regulation of fibroblast proliferationIEAbiological_process
GO:0048286Lung alveolus developmentIEAbiological_process
GO:0048536Spleen developmentIEAbiological_process
GO:0048538Thymus developmentIDAbiological_process
GO:0048557Embryonic digestive tract morphogenesisIEAbiological_process
GO:0048754Branching morphogenesis of an epithelial tubeIDAbiological_process
GO:0048807Female genitalia morphogenesisIEAbiological_process
GO:0048808Male genitalia morphogenesisIEAbiological_process
GO:0050671Positive regulation of lymphocyte proliferationIDAbiological_process
GO:0050673Epithelial cell proliferationIDAbiological_process
GO:0050674Urothelial cell proliferationIDAbiological_process
GO:0050677Positive regulation of urothelial cell proliferationIDAbiological_process
GO:0050679Positive regulation of epithelial cell proliferationIDA IEAbiological_process
GO:0050731Positive regulation of peptidyl-tyrosine phosphorylationIDAbiological_process
GO:0050872White fat cell differentiationIEAbiological_process
GO:0050918Positive chemotaxisIDAbiological_process
GO:0050930Induction of positive chemotaxisIEAbiological_process
GO:0051145Smooth muscle cell differentiationIEAbiological_process
GO:0051549Positive regulation of keratinocyte migrationIDAbiological_process
GO:0060019Radial glial cell differentiationIEA ISSbiological_process
GO:0060054Positive regulation of epithelial cell proliferation involved in wound healingNASbiological_process
GO:0060174Limb bud formationIEAbiological_process
GO:0060428Lung epithelium developmentIDAbiological_process
GO:0060430Lung saccule developmentIMPbiological_process
GO:0060436Bronchiole morphogenesisIEAbiological_process
GO:0060441Epithelial tube branching involved in lung morphogenesisIEAbiological_process
GO:0060447Bud outgrowth involved in lung branchingIDAbiological_process
GO:0060496Mesenchymal-epithelial cell signaling involved in lung developmentIEAbiological_process
GO:0060510Type II pneumocyte differentiationIEAbiological_process
GO:0060595Fibroblast growth factor receptor signaling pathway involved in mammary gland specificationIDA IEAbiological_process
GO:0060615Mammary gland bud formationIEAbiological_process
GO:0060661Submandibular salivary gland formationIEAbiological_process
GO:0060664Epithelial cell proliferation involved in salivary gland morphogenesisIEAbiological_process
GO:0060665Regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signalingIEAbiological_process
GO:0060667Branch elongation involved in salivary gland morphogenesisIEAbiological_process
GO:0060685Regulation of prostatic bud formationIEAbiological_process
GO:0060879Semicircular canal fusionIEAbiological_process
GO:0060915Mesenchymal cell differentiation involved in lung developmentIEAbiological_process
GO:0061033Secretion by lung epithelial cell involved in lung growthIDAbiological_process
GO:0061115Lung proximal/distal axis specificationIEAbiological_process
GO:0070075Tear secretionIMPbiological_process
GO:0070352Positive regulation of white fat cell proliferationIEAbiological_process
GO:0070371ERK1 and ERK2 cascadeIDAbiological_process
GO:0070374Positive regulation of ERK1 and ERK2 cascadeIDA IEAbiological_process
GO:0070384Harderian gland developmentIEAbiological_process
GO:0071157Negative regulation of cell cycle arrestIDAbiological_process
GO:0071338Positive regulation of hair follicle cell proliferationIDAbiological_process
GO:0090263Positive regulation of canonical Wnt signaling pathwayIEAbiological_process
GO:2001240Negative regulation of extrinsic apoptotic signaling pathway in absence of ligandIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.50645823110.22125385430.99999024730.9050323132

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2527888444
GSE13712_SHEARDown-0.0335845401
GSE13712_STATICUp0.0177458866
GSE19018Down-0.0924828740
GSE19899_A1Up0.0872826812
GSE19899_A2Up0.0619260387
PubMed_21979375_A1Down-0.1734000022
PubMed_21979375_A2Up0.0437779807
GSE35957Down-0.1336808903
GSE36640Up0.0636702803
GSE54402Down-0.1194428655
GSE9593Up0.0996017368
GSE43922Up0.0085256343
GSE24585Down-0.2644326676
GSE37065Up1.1568145508
GSE28863_A1Down-0.1627414684
GSE28863_A2Down-1.1135697214
GSE28863_A3Up0.2730181019
GSE28863_A4Up0.1285721645
GSE48662Down-0.0365480702

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018544MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.