HCSGD entry for FGF6

1. General information

Official gene symbolFGF6
Entrez ID2251
Gene full namefibroblast growth factor 6
Other gene symbolsHBGF-6 HST2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001502Cartilage condensationIEAbiological_process
GO:0001525AngiogenesisIEAbiological_process
GO:0005104Fibroblast growth factor receptor bindingIEAmolecular_function
GO:0005576Extracellular regionIEA TAScellular_component
GO:0005615Extracellular spaceIEAcellular_component
GO:0007165Signal transductionTASbiological_process
GO:0007173Epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0007267Cell-cell signalingTASbiological_process
GO:0008083Growth factor activityIEAmolecular_function
GO:0008283Cell proliferationTASbiological_process
GO:0008284Positive regulation of cell proliferationIGIbiological_process
GO:0008286Insulin receptor signaling pathwayTASbiological_process
GO:0008543Fibroblast growth factor receptor signaling pathwayIEA IGI TASbiological_process
GO:0038095Fc-epsilon receptor signaling pathwayTASbiological_process
GO:0042383SarcolemmaIEAcellular_component
GO:0045087Innate immune responseTASbiological_process
GO:0045445Myoblast differentiationIEAbiological_process
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0048015Phosphatidylinositol-mediated signalingTASbiological_process
GO:0051781Positive regulation of cell divisionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.32412034880.92035223210.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0336873070
GSE13712_SHEARDown-0.0436122875
GSE13712_STATICUp0.4782826608
GSE19018Up0.0975714474
GSE19899_A1Up0.1174342406
GSE19899_A2Up0.1781263494
PubMed_21979375_A1Down-0.1093166862
PubMed_21979375_A2Down-0.0348726869
GSE35957Up0.3992998935
GSE36640Up0.1006252123
GSE54402Down-0.2552517286
GSE9593Up0.2015767584
GSE43922Up0.0694761521
GSE24585Down-0.0784869786
GSE37065Down-0.1431348978
GSE28863_A1Up0.0234789781
GSE28863_A2Up0.0032376204
GSE28863_A3Up0.2815903514
GSE28863_A4Up0.1425549130
GSE48662Up0.0127955771

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

18488334OBJECTIVE: To investigate the expressions of the aging gene P16(ink4a) and anti-aging gene HST2 in benign prostatic hyperplasia (BPH)
18488334RESULTS: P16(ink4a) mRNA, rather than HST2, was expressed in the BPH and normal prostate tissues
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