HCSGD entry for FGF5
1. General information
| Official gene symbol | FGF5 |
|---|---|
| Entrez ID | 2250 |
| Gene full name | fibroblast growth factor 5 |
| Other gene symbols | HBGF-5 Smag-82 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005104 | Fibroblast growth factor receptor binding | IDA IEA | molecular_function |
| GO:0005576 | Extracellular region | IEA TAS | cellular_component |
| GO:0005615 | Extracellular space | TAS | cellular_component |
| GO:0007173 | Epidermal growth factor receptor signaling pathway | TAS | biological_process |
| GO:0007267 | Cell-cell signaling | TAS | biological_process |
| GO:0007399 | Nervous system development | TAS | biological_process |
| GO:0008083 | Growth factor activity | IEA | molecular_function |
| GO:0008283 | Cell proliferation | TAS | biological_process |
| GO:0008284 | Positive regulation of cell proliferation | IDA IGI | biological_process |
| GO:0008286 | Insulin receptor signaling pathway | TAS | biological_process |
| GO:0008543 | Fibroblast growth factor receptor signaling pathway | IDA IEA IGI TAS | biological_process |
| GO:0010001 | Glial cell differentiation | IEA | biological_process |
| GO:0023019 | Signal transduction involved in regulation of gene expression | IEA | biological_process |
| GO:0038095 | Fc-epsilon receptor signaling pathway | TAS | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0048011 | Neurotrophin TRK receptor signaling pathway | TAS | biological_process |
| GO:0048015 | Phosphatidylinositol-mediated signaling | TAS | biological_process |
| GO:0051781 | Positive regulation of cell division | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0880630523 | 0.0065601801 | 0.6231034677 | 0.1636646226 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4537518716 |
| GSE13712_SHEAR | Up | 0.7278542654 |
| GSE13712_STATIC | Up | 1.9833132951 |
| GSE19018 | Down | -1.1319570944 |
| GSE19899_A1 | Down | -1.8874361513 |
| GSE19899_A2 | Down | -0.8856867295 |
| PubMed_21979375_A1 | Down | -1.1937140576 |
| PubMed_21979375_A2 | Down | -1.2604192782 |
| GSE35957 | Down | -0.9621562122 |
| GSE36640 | Down | -0.3531810448 |
| GSE54402 | Down | -0.4431864370 |
| GSE9593 | Up | 0.2257271118 |
| GSE43922 | Down | -0.3183142232 |
| GSE24585 | Up | 0.9167978193 |
| GSE37065 | Up | 0.1026464264 |
| GSE28863_A1 | Down | -0.2614223052 |
| GSE28863_A2 | Up | 0.8117065996 |
| GSE28863_A3 | Down | -0.4174176643 |
| GSE28863_A4 | Up | 0.1907516494 |
| GSE48662 | Down | -0.6071357307 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022485 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-15b-5p | MIMAT0000417 | MIRT046529 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
