HCSGD entry for GPC4
1. General information
| Official gene symbol | GPC4 |
|---|---|
| Entrez ID | 2239 |
| Gene full name | glypican 4 |
| Other gene symbols | K-glypican |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001523 | Retinoid metabolic process | TAS | biological_process |
| GO:0005578 | Proteinaceous extracellular matrix | IEA | cellular_component |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0005796 | Golgi lumen | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IEA TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0006024 | Glycosaminoglycan biosynthetic process | TAS | biological_process |
| GO:0006027 | Glycosaminoglycan catabolic process | TAS | biological_process |
| GO:0007603 | Phototransduction, visible light | TAS | biological_process |
| GO:0008283 | Cell proliferation | TAS | biological_process |
| GO:0009653 | Anatomical structure morphogenesis | TAS | biological_process |
| GO:0009897 | External side of plasma membrane | IDA | cellular_component |
| GO:0030203 | Glycosaminoglycan metabolic process | TAS | biological_process |
| GO:0030204 | Chondroitin sulfate metabolic process | TAS | biological_process |
| GO:0031225 | Anchored component of membrane | IEA | cellular_component |
| GO:0043202 | Lysosomal lumen | TAS | cellular_component |
| GO:0043395 | Heparan sulfate proteoglycan binding | IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1516798868 | 0.0435224232 | 0.7773298871 | 0.3927163867 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2976855882 |
| GSE13712_SHEAR | Up | 0.0810323899 |
| GSE13712_STATIC | Up | 0.1629386018 |
| GSE19018 | Down | -1.4113292600 |
| GSE19899_A1 | Down | -0.1399675528 |
| GSE19899_A2 | Down | -0.6890689504 |
| PubMed_21979375_A1 | Down | -0.1472962756 |
| PubMed_21979375_A2 | Down | -0.1045474272 |
| GSE35957 | Up | 1.6834220777 |
| GSE36640 | Down | -0.2339714428 |
| GSE54402 | Down | -0.6468538631 |
| GSE9593 | Up | 1.0099921695 |
| GSE43922 | Down | -0.1457196369 |
| GSE24585 | Down | -0.4014516918 |
| GSE37065 | Up | 0.2360997465 |
| GSE28863_A1 | Up | 0.1019833988 |
| GSE28863_A2 | Up | 0.0607789707 |
| GSE28863_A3 | Up | 0.6600715183 |
| GSE28863_A4 | Down | -0.0423804321 |
| GSE48662 | Up | 0.6235731618 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-142-3p | MIMAT0000434 | MIRT021567 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024432 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026559 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029649 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
