HCSGD entry for LRWD1
1. General information
| Official gene symbol | LRWD1 |
|---|---|
| Entrez ID | 222229 |
| Gene full name | leucine-rich repeats and WD repeat domain containing 1 |
| Other gene symbols | CENP-33 ORCA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003682 | Chromatin binding | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005664 | Nuclear origin of replication recognition complex | IDA | cellular_component |
| GO:0005721 | Centromeric heterochromatin | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005815 | Microtubule organizing center | IEA | cellular_component |
| GO:0006270 | DNA replication initiation | TAS | biological_process |
| GO:0006325 | Chromatin organization | IMP | biological_process |
| GO:0008327 | Methyl-CpG binding | IDA | molecular_function |
| GO:0016568 | Chromatin modification | IEA | biological_process |
| GO:0031933 | Telomeric heterochromatin | IDA | cellular_component |
| GO:0035064 | Methylated histone residue binding | IDA | molecular_function |
| GO:0071169 | Establishment of protein localization to chromatin | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9770113636 | 0.4165404582 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | - | - |
| GSE13712_SHEAR | - | - |
| GSE13712_STATIC | - | - |
| GSE19018 | - | - |
| GSE19899_A1 | - | - |
| GSE19899_A2 | - | - |
| PubMed_21979375_A1 | - | - |
| PubMed_21979375_A2 | - | - |
| GSE35957 | - | - |
| GSE36640 | - | - |
| GSE54402 | - | - |
| GSE9593 | - | - |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Down | -0.3451943420 |
| GSE28863_A2 | Up | 0.1125149145 |
| GSE28863_A3 | Down | -0.0811982327 |
| GSE28863_A4 | Down | -0.0397707538 |
| GSE48662 | Down | -0.0340513760 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023895 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
