HCSGD entry for FCN2
1. General information
| Official gene symbol | FCN2 |
|---|---|
| Entrez ID | 2220 |
| Gene full name | ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) |
| Other gene symbols | EBP-37 FCNL P35 ficolin-2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001867 | Complement activation, lectin pathway | TAS | biological_process |
| GO:0003823 | Antigen binding | TAS | molecular_function |
| GO:0005509 | Calcium ion binding | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005581 | Collagen | IEA | cellular_component |
| GO:0006956 | Complement activation | TAS | biological_process |
| GO:0008228 | Opsonization | TAS | biological_process |
| GO:0030246 | Carbohydrate binding | TAS | molecular_function |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0048306 | Calcium-dependent protein binding | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6939515634 | 0.8319756202 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0769076007 |
| GSE13712_SHEAR | Down | -0.0031925415 |
| GSE13712_STATIC | Down | -0.0764785010 |
| GSE19018 | Up | 0.2165172228 |
| GSE19899_A1 | Up | 0.0068405624 |
| GSE19899_A2 | Up | 0.1978911326 |
| PubMed_21979375_A1 | Down | -0.1297484892 |
| PubMed_21979375_A2 | Down | -0.0273746942 |
| GSE35957 | Up | 0.0686830253 |
| GSE36640 | Up | 0.0466075561 |
| GSE54402 | Down | -0.0480848295 |
| GSE9593 | Up | 0.0711136506 |
| GSE43922 | Up | 0.1218599447 |
| GSE24585 | Down | -0.0685376138 |
| GSE37065 | Down | -0.0374914059 |
| GSE28863_A1 | Down | -0.0964297165 |
| GSE28863_A2 | Down | -0.1681971320 |
| GSE28863_A3 | Up | 0.2826445114 |
| GSE28863_A4 | Up | 0.1440785409 |
| GSE48662 | Down | -0.0009458528 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029624 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
