HCSGD entry for BRAT1
1. General information
| Official gene symbol | BRAT1 |
|---|---|
| Entrez ID | 221927 |
| Gene full name | BRCA1-associated ATM activator 1 |
| Other gene symbols | BAAT1 C7orf27 RMFSL |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0010212 | Response to ionizing radiation | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1760234376 | 0.6659355116 | 0.8236513509 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1166115297 |
| GSE13712_SHEAR | Down | -0.4421216105 |
| GSE13712_STATIC | Down | -0.2943841477 |
| GSE19018 | Up | 0.1511205399 |
| GSE19899_A1 | Up | 0.1497423435 |
| GSE19899_A2 | Up | 0.5924106760 |
| PubMed_21979375_A1 | Up | 0.5103422041 |
| PubMed_21979375_A2 | Up | 2.0849252114 |
| GSE35957 | Down | -0.4403446924 |
| GSE36640 | Up | 0.1313112804 |
| GSE54402 | Up | 0.1113358213 |
| GSE9593 | Down | -0.1514013409 |
| GSE43922 | Up | 0.0775891390 |
| GSE24585 | Down | -0.0855063977 |
| GSE37065 | Down | -0.0994338259 |
| GSE28863_A1 | Down | -0.0158712369 |
| GSE28863_A2 | Up | 0.0843338595 |
| GSE28863_A3 | Up | 0.2119831437 |
| GSE28863_A4 | Down | -0.0760527702 |
| GSE48662 | Down | -0.2212144450 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT016937 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-130b-5p | MIMAT0004680 | MIRT038295 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041857 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-27b-3p | MIMAT0000419 | MIRT046230 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-15b-5p | MIMAT0000417 | MIRT046452 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-27a-3p | MIMAT0000084 | MIRT050026 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051289 | CLASH | Functional MTI (Weak) | 23622248 |
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