HCSGD entry for PRPS1L1
1. General information
| Official gene symbol | PRPS1L1 |
|---|---|
| Entrez ID | 221823 |
| Gene full name | phosphoribosyl pyrophosphate synthetase 1-like 1 |
| Other gene symbols | PRPS1 PRPS3 PRPSL PRS-III |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000287 | Magnesium ion binding | IEA | molecular_function |
| GO:0004749 | Ribose phosphate diphosphokinase activity | ISS NAS | molecular_function |
| GO:0005524 | ATP binding | ISS | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0006015 | 5-phosphoribose 1-diphosphate biosynthetic process | IEA | biological_process |
| GO:0009156 | Ribonucleoside monophosphate biosynthetic process | IEA | biological_process |
| GO:0009165 | Nucleotide biosynthetic process | IEA | biological_process |
| GO:0016301 | Kinase activity | IEA | molecular_function |
| GO:0042803 | Protein homodimerization activity | ISS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9292598571 | 0.1641217051 | 0.9999902473 | 0.7831485497 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1288625295 |
| GSE13712_SHEAR | Down | -0.2464687682 |
| GSE13712_STATIC | Up | 0.0372057830 |
| GSE19018 | Down | -0.0107560260 |
| GSE19899_A1 | Up | 0.0046058966 |
| GSE19899_A2 | Down | -0.1562199534 |
| PubMed_21979375_A1 | Down | -0.0995966160 |
| PubMed_21979375_A2 | Down | -0.1906681361 |
| GSE35957 | Up | 0.1035972526 |
| GSE36640 | Up | 0.1749400788 |
| GSE54402 | Up | 0.1216495515 |
| GSE9593 | Up | 0.0869604869 |
| GSE43922 | Up | 0.0159805458 |
| GSE24585 | Down | -0.2508550702 |
| GSE37065 | Down | -0.0214780622 |
| GSE28863_A1 | Down | -0.5735561681 |
| GSE28863_A2 | Down | -0.2411984488 |
| GSE28863_A3 | Down | -0.0530200355 |
| GSE28863_A4 | Down | -0.0424619779 |
| GSE48662 | Down | -0.2932204356 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
