HCSGD entry for LEMD2
1. General information
| Official gene symbol | LEMD2 |
|---|---|
| Entrez ID | 221496 |
| Gene full name | LEM domain containing 2 |
| Other gene symbols | NET25 dJ482C21.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005639 | Integral component of nuclear inner membrane | IDA IEA | cellular_component |
| GO:0031965 | Nuclear membrane | IDA IEA | cellular_component |
| GO:0035914 | Skeletal muscle cell differentiation | IEA IGI | biological_process |
| GO:0043409 | Negative regulation of MAPK cascade | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5848151704 | 0.2743199005 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1480180979 |
| GSE13712_SHEAR | Down | -0.0463124020 |
| GSE13712_STATIC | Down | -0.0943985135 |
| GSE19018 | Down | -0.1138692717 |
| GSE19899_A1 | Down | -0.3996848329 |
| GSE19899_A2 | Up | 0.4575726631 |
| PubMed_21979375_A1 | Up | 0.1345748791 |
| PubMed_21979375_A2 | Up | 1.0889804706 |
| GSE35957 | Down | -0.4522668700 |
| GSE36640 | Up | 0.2461256369 |
| GSE54402 | Up | 0.0674597838 |
| GSE9593 | Up | 0.1536397461 |
| GSE43922 | Up | 0.0408887544 |
| GSE24585 | Down | -0.3491030239 |
| GSE37065 | Down | -0.0514322477 |
| GSE28863_A1 | Up | 0.0082337700 |
| GSE28863_A2 | Up | 0.0347752938 |
| GSE28863_A3 | Down | -0.3684897633 |
| GSE28863_A4 | Down | -0.1896439572 |
| GSE48662 | Up | 0.2225440359 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-23a-3p | MIMAT0000078 | MIRT050421 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
