HCSGD entry for SKA3
1. General information
| Official gene symbol | SKA3 |
|---|---|
| Entrez ID | 221150 |
| Gene full name | spindle and kinetochore associated complex subunit 3 |
| Other gene symbols | C13orf3 RAMA1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000940 | Condensed chromosome outer kinetochore | IDA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005876 | Spindle microtubule | IDA | cellular_component |
| GO:0007059 | Chromosome segregation | IMP | biological_process |
| GO:0007067 | Mitosis | IMP | biological_process |
| GO:0031110 | Regulation of microtubule polymerization or depolymerization | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9772467535 | 0.0000482580 | 0.9999902473 | 0.0114692982 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3451981533 |
| GSE13712_SHEAR | Up | 0.1854195434 |
| GSE13712_STATIC | Down | -0.2670343967 |
| GSE19018 | Up | 0.0695027435 |
| GSE19899_A1 | Down | -0.8390107901 |
| GSE19899_A2 | Down | -4.0629600995 |
| PubMed_21979375_A1 | Down | -2.0638204662 |
| PubMed_21979375_A2 | Down | -4.8675261974 |
| GSE35957 | Down | -1.6028406660 |
| GSE36640 | Down | -4.6962114320 |
| GSE54402 | Down | -0.3653490770 |
| GSE9593 | Down | -1.2553483700 |
| GSE43922 | Down | -2.9199916453 |
| GSE24585 | Down | -0.1368292589 |
| GSE37065 | Down | -0.9728863432 |
| GSE28863_A1 | Down | -0.5108467144 |
| GSE28863_A2 | Up | 0.1077538901 |
| GSE28863_A3 | Down | -0.1880855023 |
| GSE28863_A4 | Up | 0.3317289764 |
| GSE48662 | Down | -1.3783405828 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041438 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052469 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
