HCSGD entry for ALKBH3

1. General information

Official gene symbolALKBH3
Entrez ID221120
Gene full namealkB, alkylation repair homolog 3 (E. coli)
Other gene symbolsABH3 DEPC-1 DEPC1 PCA1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005739MitochondrionIDAcellular_component
GO:0006281DNA repairIDA TASbiological_process
GO:0006307DNA dealkylation involved in DNA repairIDA TASbiological_process
GO:0008198Ferrous iron bindingIDAmolecular_function
GO:0008283Cell proliferationIMPbiological_process
GO:0016706Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donorsIEAmolecular_function
GO:0031418L-ascorbic acid bindingIEAmolecular_function
GO:0035552Oxidative single-stranded DNA demethylationIDA IMPbiological_process
GO:0043734DNA-N1-methyladenine dioxygenase activityIDA IMPmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.97653831920.02948198780.99999024730.3256380193

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2129270602
GSE13712_SHEARDown-0.0681825399
GSE13712_STATICDown-0.4618490069
GSE19018Down-0.0355057160
GSE19899_A1Down-0.7308098700
GSE19899_A2Down-0.5782179232
PubMed_21979375_A1Up0.3490255359
PubMed_21979375_A2Down-0.6179048197
GSE35957Down-0.4076899799
GSE36640Down-0.7027317567
GSE54402Down-0.2409560028
GSE9593Up0.2033931100
GSE43922Down-0.1654475241
GSE24585Down-0.2668738433
GSE37065Down-0.1499772841
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.0874918385

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Vitamin CDB00126 NUTR00001 | APRD00084 | EXPT00568 | DB09541

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.