HCSGD entry for RASGEF1A
1. General information
| Official gene symbol | RASGEF1A |
|---|---|
| Entrez ID | 221002 |
| Gene full name | RasGEF domain family, member 1A |
| Other gene symbols | CG4853 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005085 | Guanyl-nucleotide exchange factor activity | IEA | molecular_function |
| GO:0005088 | Ras guanyl-nucleotide exchange factor activity | IDA | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0007264 | Small GTPase mediated signal transduction | IEA | biological_process |
| GO:0016477 | Cell migration | IDA | biological_process |
| GO:0032318 | Regulation of Ras GTPase activity | IDA | biological_process |
| GO:0043087 | Regulation of GTPase activity | IDA | biological_process |
| GO:0046579 | Positive regulation of Ras protein signal transduction | IDA | biological_process |
| GO:0051056 | Regulation of small GTPase mediated signal transduction | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1726591049 | 0.8959919760 | 0.8157530605 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0144335678 |
| GSE13712_SHEAR | Up | 1.0577675437 |
| GSE13712_STATIC | Up | 1.1624933258 |
| GSE19018 | Up | 0.0292519966 |
| GSE19899_A1 | Down | -0.0552311439 |
| GSE19899_A2 | Up | 0.2644730292 |
| PubMed_21979375_A1 | Down | -0.2007142637 |
| PubMed_21979375_A2 | Down | -0.1514044087 |
| GSE35957 | Up | 0.0068466759 |
| GSE36640 | Up | 0.0441656682 |
| GSE54402 | Up | 0.0524426033 |
| GSE9593 | Up | 0.1177624186 |
| GSE43922 | Up | 0.0391684854 |
| GSE24585 | Down | -0.0662935179 |
| GSE37065 | Up | 0.0041430801 |
| GSE28863_A1 | Down | -0.1176998141 |
| GSE28863_A2 | Down | -0.0773811014 |
| GSE28863_A3 | Up | 0.3635271056 |
| GSE28863_A4 | Up | 0.0731786978 |
| GSE48662 | Up | 0.0615592065 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017006 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 24478790 | 2; and RASGEF1A, HNRNPF, ANF487, CSTF2T, and PRKG1 at 10q11 |
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