HCSGD entry for FCGR1B

1. General information

Official gene symbolFCGR1B
Entrez ID2210
Gene full nameFc fragment of IgG, high affinity Ib, receptor (CD64)
Other gene symbolsCD64b IGFRB
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002474Antigen processing and presentation of peptide antigen via MHC class ITASbiological_process
GO:0002479Antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependentTASbiological_process
GO:0005886Plasma membraneNAS TAScellular_component
GO:0006955Immune responseNASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0019763Immunoglobulin receptor activityNASmolecular_function
GO:0019864IgG bindingIEAmolecular_function
GO:0030669Clathrin-coated endocytic vesicle membraneTAScellular_component
GO:0031901Early endosome membraneTAScellular_component
GO:0038093Fc receptor signaling pathwayNASbiological_process
GO:0042590Antigen processing and presentation of exogenous peptide antigen via MHC class ITASbiological_process
GO:0060333Interferon-gamma-mediated signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.62291832000.88771092660.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0760174023
GSE13712_SHEARDown-0.0492693773
GSE13712_STATICDown-0.0527596856
GSE19018Up0.0141775058
GSE19899_A1Up0.0275091210
GSE19899_A2Up0.1872596557
PubMed_21979375_A1Down-0.0727893020
PubMed_21979375_A2Up0.0658000317
GSE35957Down-0.0522147693
GSE36640Up0.4147304630
GSE54402Down-0.0198429518
GSE9593Up0.0321338568
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.0890544573

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Immune Globulin HumanDB00028 BTD00091 | BIOD00091

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029614MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.