HCSGD entry for FCGR1A

1. General information

Official gene symbolFCGR1A
Entrez ID2209
Gene full nameFc fragment of IgG, high affinity Ia, receptor (CD64)
Other gene symbolsCD64 CD64A FCRI IGFR1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002474Antigen processing and presentation of peptide antigen via MHC class ITASbiological_process
GO:0002479Antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependentTASbiological_process
GO:0005057Receptor signaling protein activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneIDA TAScellular_component
GO:0006911Phagocytosis, engulfmentTASbiological_process
GO:0006955Immune responseTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0019864IgG bindingIEAmolecular_function
GO:0030669Clathrin-coated endocytic vesicle membraneTAScellular_component
GO:0031901Early endosome membraneTAScellular_component
GO:0035556Intracellular signal transductionTASbiological_process
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosisTASbiological_process
GO:0042590Antigen processing and presentation of exogenous peptide antigen via MHC class ITASbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0060333Interferon-gamma-mediated signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.35154876330.92240562290.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1235386877
GSE13712_SHEARDown-0.0251984676
GSE13712_STATICDown-0.1262713389
GSE19018Up0.2769125808
GSE19899_A1Up0.1843744719
GSE19899_A2Down-0.0510974815
PubMed_21979375_A1Up0.2947973479
PubMed_21979375_A2Up0.2073473966
GSE35957Up0.0417640228
GSE36640Up0.2117107627
GSE54402Up0.1162623670
GSE9593Up0.2936316446
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Down-0.0443174351
GSE28863_A2Down-0.0404883476
GSE28863_A3Up0.1788237809
GSE28863_A4Down-0.0897361504
GSE48662--

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

CetuximabDB00002 BTD00071 | BIOD00071
EtanerceptDB00005 BTD00052 | BIOD00052
Immune Globulin HumanDB00028 BTD00091 | BIOD00091
AdalimumabDB00051 BTD00049 | BIOD00049
AbciximabDB00054 BTD00041 | BIOD00041
Gemtuzumab ozogamicinDB00056 BTD00077 | BIOD00077
TrastuzumabDB00072 BTD00098 | BIOD00098
RituximabDB00073 BTD00014 | BIOD00014
BasiliximabDB00074 BTD00073 | BIOD00073
MuromonabDB00075 BTD00005 | BIOD00005
Ibritumomab tiuxetanDB00078 BTD00069 | BIOD00069
TositumomabDB00081 BTD00085 | BIOD00085
AlemtuzumabDB00087 BTD00109 | BIOD00109
AlefaceptDB00092 BTD00055 | BIOD00055
EfalizumabDB00095 BTD00074 | BIOD00074
NatalizumabDB00108 BTD00083 | BIOD00083
PalivizumabDB00110 BTD00097 | BIOD00097
DaclizumabDB00111 BTD00007 | BIOD00007
BevacizumabDB00112 BTD00087 | BIOD00087
PorfimerDB00707 APRD00078
Methyl aminolevulinateDB00992 APRD01105

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.