HCSGD entry for MS4A2
1. General information
| Official gene symbol | MS4A2 |
|---|---|
| Entrez ID | 2206 |
| Gene full name | membrane-spanning 4-domains, subfamily A, member 2 |
| Other gene symbols | APY ATOPY FCER1B FCERI IGEL IGER IGHER MS4A1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005768 | Endosome | IEA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | IEA NAS | cellular_component |
| GO:0006954 | Inflammatory response | IEA | biological_process |
| GO:0006955 | Immune response | IMP | biological_process |
| GO:0007202 | Activation of phospholipase C activity | IEA | biological_process |
| GO:0007205 | Protein kinase C-activating G-protein coupled receptor signaling pathway | IEA | biological_process |
| GO:0009897 | External side of plasma membrane | IEA | cellular_component |
| GO:0019863 | IgE binding | IEA | molecular_function |
| GO:0019901 | Protein kinase binding | IEA | molecular_function |
| GO:0032998 | Fc-epsilon receptor I complex | IEA | cellular_component |
| GO:0038095 | Fc-epsilon receptor signaling pathway | TAS | biological_process |
| GO:0042169 | SH2 domain binding | IEA | molecular_function |
| GO:0043306 | Positive regulation of mast cell degranulation | IEA | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0045121 | Membrane raft | IEA | cellular_component |
| GO:0050663 | Cytokine secretion | IEA | biological_process |
| GO:0051219 | Phosphoprotein binding | IEA | molecular_function |
| GO:0051279 | Regulation of release of sequestered calcium ion into cytosol | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9235151362 | 0.5856008890 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1088152995 |
| GSE13712_SHEAR | Down | -0.1290332328 |
| GSE13712_STATIC | Down | -0.1629736442 |
| GSE19018 | Down | -0.0189467069 |
| GSE19899_A1 | Up | 0.0057126391 |
| GSE19899_A2 | Up | 0.0447813802 |
| PubMed_21979375_A1 | Up | 0.1740967593 |
| PubMed_21979375_A2 | Down | -0.1151322319 |
| GSE35957 | Up | 0.0780398870 |
| GSE36640 | Down | -0.0041229218 |
| GSE54402 | Down | -0.0017821266 |
| GSE9593 | Down | -0.0768245271 |
| GSE43922 | Up | 0.0212711425 |
| GSE24585 | Down | -0.1318573238 |
| GSE37065 | Up | 0.0508396833 |
| GSE28863_A1 | Down | -0.0099791601 |
| GSE28863_A2 | Down | -0.0220001919 |
| GSE28863_A3 | Down | -0.0252988338 |
| GSE28863_A4 | Up | 0.0185636931 |
| GSE48662 | Up | 0.0370674631 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Omalizumab | DB00043 | BTD00081 | BIOD00081 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017962 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
