HCSGD entry for ABCB7
1. General information
| Official gene symbol | ABCB7 |
|---|---|
| Entrez ID | 22 |
| Gene full name | ATP-binding cassette, sub-family B (MDR/TAP), member 7 |
| Other gene symbols | ABC7 ASAT Atm1p EST140535 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | IDA TAS | cellular_component |
| GO:0006200 | ATP catabolic process | IBA TAS | biological_process |
| GO:0006810 | Transport | TAS | biological_process |
| GO:0006879 | Cellular iron ion homeostasis | IBA | biological_process |
| GO:0015232 | Heme transporter activity | TAS | molecular_function |
| GO:0015886 | Heme transport | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IBA IEA | cellular_component |
| GO:0042626 | ATPase activity, coupled to transmembrane movement of substances | IBA IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0051181 | Cofactor transport | TAS | biological_process |
| GO:0055085 | Transmembrane transport | IBA TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9513528779 | 0.0422797006 | 0.9999902473 | 0.3869415855 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1640157748 |
| GSE13712_SHEAR | Down | -0.2535456128 |
| GSE13712_STATIC | Down | -0.2631633752 |
| GSE19018 | Up | 0.0402432105 |
| GSE19899_A1 | Down | -0.0136513414 |
| GSE19899_A2 | Down | -0.2616267054 |
| PubMed_21979375_A1 | Up | 0.6854943440 |
| PubMed_21979375_A2 | Up | 0.2010993841 |
| GSE35957 | Down | -0.4707907026 |
| GSE36640 | Down | -0.3641833028 |
| GSE54402 | Down | -0.1507249019 |
| GSE9593 | Down | -0.3785929259 |
| GSE43922 | Down | -0.1705476096 |
| GSE24585 | Up | 0.1032688466 |
| GSE37065 | Down | -0.1409987482 |
| GSE28863_A1 | Up | 0.0029412447 |
| GSE28863_A2 | Down | -0.0377784933 |
| GSE28863_A3 | Down | -1.1329320043 |
| GSE28863_A4 | Up | 0.0045577686 |
| GSE48662 | Down | -0.2134684001 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-148b-3p | MIMAT0000759 | MIRT019397 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-1 | MIMAT0000416 | MIRT023677 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-935 | MIMAT0004978 | MIRT036642 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-195-5p | MIMAT0000461 | MIRT044862 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047592 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-26a-5p | MIMAT0000082 | MIRT050056 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-3p | MIMAT0000071 | MIRT050748 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051202 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
