HCSGD entry for PATL1
1. General information
| Official gene symbol | PATL1 |
|---|---|
| Entrez ID | 219988 |
| Gene full name | protein associated with topoisomerase II homolog 1 (yeast) |
| Other gene symbols | Pat1b hPat1b |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000288 | Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | TAS | biological_process |
| GO:0000290 | Deadenylation-dependent decapping of nuclear-transcribed mRNA | IDA | biological_process |
| GO:0000932 | Cytoplasmic mRNA processing body | IDA | cellular_component |
| GO:0003723 | RNA binding | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0008266 | Poly(U) RNA binding | IDA | molecular_function |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016070 | RNA metabolic process | TAS | biological_process |
| GO:0016071 | MRNA metabolic process | TAS | biological_process |
| GO:0016605 | PML body | IEA | cellular_component |
| GO:0016607 | Nuclear speck | IEA | cellular_component |
| GO:0030014 | CCR4-NOT complex | IDA | cellular_component |
| GO:0033962 | Cytoplasmic mRNA processing body assembly | IDA | biological_process |
| GO:0034046 | Poly(G) binding | IDA | molecular_function |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0043928 | Exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5486897990 | 0.2422124501 | 0.9999902473 | 0.9478675736 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0940899787 |
| GSE13712_SHEAR | Up | 0.2400495850 |
| GSE13712_STATIC | Up | 0.0765911979 |
| GSE19018 | Down | -0.0879579337 |
| GSE19899_A1 | Down | -0.1035650207 |
| GSE19899_A2 | Down | -0.2014820980 |
| PubMed_21979375_A1 | Down | -0.3416546719 |
| PubMed_21979375_A2 | Down | -0.0329822459 |
| GSE35957 | Down | -0.6805401650 |
| GSE36640 | Down | -0.9270205108 |
| GSE54402 | Up | 0.1045081123 |
| GSE9593 | Up | 0.4367506904 |
| GSE43922 | Down | -0.1970709146 |
| GSE24585 | Down | -0.0892841061 |
| GSE37065 | Up | 0.2719876868 |
| GSE28863_A1 | Up | 0.2379668362 |
| GSE28863_A2 | Up | 0.5765216617 |
| GSE28863_A3 | Down | -0.0820533590 |
| GSE28863_A4 | Up | 0.1132670628 |
| GSE48662 | Down | -0.3417410750 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031120 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-196a-5p | MIMAT0000226 | MIRT048252 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
