HCSGD entry for RTKN2
1. General information
| Official gene symbol | RTKN2 |
|---|---|
| Entrez ID | 219790 |
| Gene full name | rhotekin 2 |
| Other gene symbols | PLEKHK1 bA531F24.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0007165 | Signal transduction | IEA | biological_process |
| GO:0008284 | Positive regulation of cell proliferation | IEA | biological_process |
| GO:0030097 | Hemopoiesis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8139750389 | 0.0528573990 | 0.9999902473 | 0.4338196445 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0773146802 |
| GSE13712_SHEAR | Down | -0.2495071682 |
| GSE13712_STATIC | Down | -0.0243387361 |
| GSE19018 | Down | -0.1540511603 |
| GSE19899_A1 | Down | -0.0396628715 |
| GSE19899_A2 | Down | -0.4002792282 |
| PubMed_21979375_A1 | Down | -0.1672880829 |
| PubMed_21979375_A2 | Down | -0.3185353403 |
| GSE35957 | Down | -0.1737625773 |
| GSE36640 | Down | -0.3502560631 |
| GSE54402 | Down | -0.4433723593 |
| GSE9593 | Up | 0.0559813832 |
| GSE43922 | Down | -0.3293407414 |
| GSE24585 | Down | -0.0696066153 |
| GSE37065 | Down | -0.1472566372 |
| GSE28863_A1 | Down | -0.4594783272 |
| GSE28863_A2 | Up | 0.8860315600 |
| GSE28863_A3 | Down | -0.1745847237 |
| GSE28863_A4 | Up | 0.5604496485 |
| GSE48662 | Down | -0.2824544713 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016449 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024839 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026703 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040583 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10b-5p | MIMAT0000254 | MIRT047409 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047538 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
